Commensal microbiota that reside primarily in the gut of mammals influence the hosts'
health to a great extent. Shaping of host immunity locally, a vital component of this influence …

Inflammatory bowel diseases (IBD), consisting of Crohn's disease and ulcerative colitis, are
important diseases of the gastrointestinal tract and are associated with a high degree of …

Recent advances in understanding how the mammalian immune system and intestinal
microbiota functionally interact have yielded novel insights for human health and disease …

The mammalian intestine is colonized by trillions of microorganisms, most of which are
bacteria that have co-evolved with the host in a symbiotic relationship. The collection of …

The diverse microbial populations constituting the intestinal microbiota promote immune
development and differentiation, but because of their complex metabolic requirements and …

The relationship between commensal microbes and their hosts has been studied for many
years. Commensal microorganisms are known to have a significant role in regulating the …

The intestinal microbiota has important metabolic and host-protective functions. Conversely
to these beneficial functions, the intestinal microbiota is thought to play a central role in the …

The commensal microbiota is in constant interaction with the immune system, teaching
immune cells to respond to antigens. Studies in mice have demonstrated that manipulation …

The commensal microbiota that inhabit different parts of the gastrointestinal (GI) tract have
been shaped by coevolution with the host species. The symbiotic relationship of the …

The impact of the gut microbiota on immune homeostasis within the gut and, importantly,
also at systemic sites has gained tremendous research interest over the last few years. The …