Impaired vitamin D signaling in endothelial cell leads to an enhanced leukocyte-endothelium interplay: implications for atherosclerosis development
M Bozic, Á Álvarez, C de Pablo, MD Sanchez-Niño… - PLoS …, 2015 - journals.plos.org
Endothelial cell activation leading to leukocyte recruitment and adhesion plays an essential
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective …
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective …
Elimination of vitamin D receptor in vascular endothelial cells alters vascular function
W Ni, SW Watts, M Ng, S Chen, DJ Glenn… - …, 2014 - Am Heart Assoc
Vitamin D deficiency has been associated with cardiovascular dysfunction. We evaluated
the role of the vitamin D receptor (VDR) in vascular endothelial function, a marker of …
the role of the vitamin D receptor (VDR) in vascular endothelial function, a marker of …
Vitamin D receptor activation reduces angiotensin-II–induced dissecting abdominal aortic aneurysm in apolipoprotein E–knockout mice
S Martorell, L Hueso, H Gonzalez-Navarro… - … and Vascular Biology, 2016 - Am Heart Assoc
Objective—Abdominal aortic aneurysm (AAA) is a vascular disorder characterized by
chronic inflammation of the aortic wall. Low concentrations of vitamin D3 are associated with …
chronic inflammation of the aortic wall. Low concentrations of vitamin D3 are associated with …
[HTML][HTML] Vitamin D and the endothelium: basic, translational and clinical research updates
Introduction and background Vitamin D deficiency has been associated with cardiovascular
diseases (CVDs) and its surrogate indicators such as endothelial dysfunction. It is an …
diseases (CVDs) and its surrogate indicators such as endothelial dysfunction. It is an …
Brief report: vitamin D deficiency is associated with endothelial dysfunction and increases type I interferon gene expression in a murine model of systemic lupus …
JA Reynolds, AZ Rosenberg, CK Smith… - Arthritis & …, 2016 - Wiley Online Library
Objective Patients with systemic lupus erythematosus (SLE) have an increased risk of
cardiovascular disease (CVD) and impaired endothelial repair. Although vitamin D …
cardiovascular disease (CVD) and impaired endothelial repair. Although vitamin D …
Role of vitamin D in atherosclerosis
It is well known that endothelium is the key vessel wall component in the initiation of the
atherogenic process. Its possible role in the later stages has been strongly suggested. 17 …
atherogenic process. Its possible role in the later stages has been strongly suggested. 17 …
Increased monocyte‐platelet aggregates and monocyte‐endothelial adhesion in healthy individuals with vitamin D deficiency
Vitamin D deficiency is a major public health problem worldwide, linked to several chronic
diseases including cardiovascular diseases. While immunomodulatory effects of vitamin D …
diseases including cardiovascular diseases. While immunomodulatory effects of vitamin D …
Vitamin D receptor signaling inhibits atherosclerosis in mice
FL Szeto, CA Reardon, D Yoon, Y Wang… - Molecular …, 2012 - academic.oup.com
Although vitamin D has been implicated in cardiovascular protection, few studies have
addressed the role of vitamin D receptor (VDR) in atherosclerosis. Here we investigate the …
addressed the role of vitamin D receptor (VDR) in atherosclerosis. Here we investigate the …
Activation of vitamin D receptor promotes VEGF and CuZn-SOD expression in endothelial cells
W Zhong, B Gu, Y Gu, LJ Groome, J Sun… - The Journal of steroid …, 2014 - Elsevier
Endothelial dysfunction associated with vitamin D deficiency has been linked to many
chronic vascular diseases. Vitamin D elicits its bioactive actions by binding to its receptor …
chronic vascular diseases. Vitamin D elicits its bioactive actions by binding to its receptor …
Vitamin D and endothelial function
Vitamin D is known to elicit a vasoprotective effect, while vitamin D deficiency is a risk factor
for endothelial dysfunction (ED). ED is characterized by reduced bioavailability of a potent …
for endothelial dysfunction (ED). ED is characterized by reduced bioavailability of a potent …