Cerebrovascular dysfunction contributes to the cognitive decline and dementia in
Alzheimer's disease (AD), and may precede cerebral amyloid angiopathy and brain …

Objective–To evaluate the integrity of the blood–brain barrier (BBB) in incident Alzheimer's
disease (AD). Materials and methods–The mean age of the 157 patients (45% men) was …

Cerebral endothelial cells and their linking tight junctions form a unique, dynamic and multi-
functional interface, the blood-brain barrier (BBB). The endothelium is regulated by …

Alzheimer's disease (AD) is the most common form of dementia, affecting millions of people
worldwide. One of the prominent causative factors of AD pathogenesis is cerebral vascular …

The vascular endothelium in the brain is an essential part of the blood-brain-barrier (BBB)
because of its very tight structure to secure a functional and molecular separation of the …

The aim of this review is to present evidence of the impact of ischemic changes in the blood–
brain barrier on the maturation of post-ischemic brain neurodegeneration with features of …

The blood-brain barrier (BBB) is a selective barrier and a functional gatekeeper for the
central nervous system (CNS), essential for maintaining brain homeostasis. The BBB is …

Blood–brain barrier (BBB) breakdown can disrupt nutrient supply and waste removal, which
affects neuronal functioning. Currently, dynamic contrast-enhanced (DCE) MRI is the …

Vascular dysfunction has a critical role in Alzheimer's disease (AD). Recent data from brain
imaging studies in humans and animal models suggest that cerebrovascular dysfunction …

Neurovascular dysfunction is an integral part of Alzheimer disease (AD). Changes in the
brain vascular system may contribute in a significant way to the onset and progression of …