Recently, new pathomorphologic information about early-stage small hepatocellular
carcinoma (HCC) and the multi-step process of human hepatocarcinogenesis has been …

Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the 2 most common
primary malignant liver tumors, with hepatocellular and bile ductular differentiation …

Context.—There is increasing evidence to support a multistep model of the process of
human hepatocarcinogenesis. Precursor lesions are characterized by the appearance of …

Over the past decade extensive studies on small early stage hepatocellular carcinomas
(HCCs) have defined their pathomorphologic features. Most early HCCs are well …

ABSTRACT Recently, an East–West consensus on the histopathologic criteria for the
diagnosis of high-grade dysplastic nodules (HGDN) versus early hepatocellular carcinoma …

Precancerous lesions that may be detected in chronically diseased, usually cirrhotic livers,
include: clusters of hepatocytes with atypia and increased proliferative rate (dysplastic foci) …

Hepatocarcinogenesis in human chronic liver diseases is a multi-step process in which
hepatic precancerous lesions progress into early hepatocellular carcinoma (HCC) and …

It has been established that small, equivocal nodular lesions such as dysplastic nodules
(DNs) and small well-differentiated hepatocellular carcinomas (early HCCs) are frequently …

Recent advances in the understanding of HCC heterogeneity have shown not only distinct
molecular classes with potential therapeutical implications but also have suggested that …

Hepatocellular carcinoma (HCC) is currently the sixth most common type of cancer with a
high mortality rate and an increasing incidence worldwide. Its etiology is usually linked to …