Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development

HJ Hallam, S Hallam, SE Rodriguez, ADT Barrett… - NPJ vaccines, 2018 - nature.com
Lassa fever (LF) is a zoonotic disease associated with acute and potentially fatal
hemorrhagic illness caused by the Lassa virus (LASV), a member of the family Arenaviridae …

Advanced vaccine candidates for Lassa fever

IS Lukashevich - Viruses, 2012 - mdpi.com
Lassa virus (LASV) is the most prominent human pathogen of the Arenaviridae. The virus is
transmitted to humans by a rodent reservoir, Mastomys natalensis, and is capable of causing …

[HTML][HTML] Vaccine platforms for the prevention of Lassa fever

J Purushotham, T Lambe, SC Gilbert - Immunology Letters, 2019 - Elsevier
Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus (LASV), which is
endemic throughout much of West Africa. The virus primarily circulates in the Mastomys …

Lassa fever—the road ahead

RF Garry - Nature Reviews Microbiology, 2023 - nature.com
Lassa virus (LASV) is endemic in the rodent populations of Sierra Leone, Nigeria and other
countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a …

Vaccine platforms to control Lassa fever

IS Lukashevich, P Pushko - Expert Review of Vaccines, 2016 - Taylor & Francis
ABSTRACT Introduction: Lassa virus (LASV), the most prominent human pathogen of the
Arenaviridae, is transmitted to humans from infected rodents and can cause Lassa Fever …

Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments

HL Murphy, H Ly - Virulence, 2021 - Taylor & Francis
Lassa fever (LF) is a deadly viral hemorrhagic disease that is endemic to West Africa. The
causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections …

A recombinant vesicular stomatitis virus-based Lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct …

D Safronetz, C Mire, K Rosenke… - PLoS neglected …, 2015 - journals.plos.org
Background Lassa virus (LASV) is endemic in several West African countries and is the
etiological agent of Lassa fever. Despite the high annual incidence and significant morbidity …

Diagnostics for Lassa fever virus: a genetically diverse pathogen found in low-resource settings

LT Mazzola, C Kelly-Cirino - BMJ Global Health, 2019 - gh.bmj.com
Lassa fever virus (LASV) causes acute viral haemorrhagic fever with symptoms similar to
those seen with Ebola virus infections. LASV is endemic to West Africa and is transmitted …

Current research for a vaccine against Lassa hemorrhagic fever virus

BM Warner, D Safronetz, DR Stein - Drug design, development and …, 2018 - Taylor & Francis
Lassa virus (LASV) is a rodent-borne arenavirus endemic to several West African countries
that causes Lassa fever (LF). LF is typically mild but it can cause severe disease …

Identification of Common CD8+ T Cell Epitopes from Lassa Fever Survivors in Nigeria and Sierra Leone

S Sakabe, JN Hartnett, N Ngo, A Goba… - Journal of …, 2020 - Am Soc Microbiol
Early and robust T cell responses have been associated with survival from Lassa fever (LF),
but the Lassa virus-specific memory responses have not been well characterized. Regions …