Nutraceutical targeting of inflammation-modulating microRNAs in severe forms of COVID-19: a novel approach to prevent the cytokine storm

M Desjarlais, M Wirth, I Lahaie, P Ruknudin… - Frontiers in …, 2020 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic has become the number one health
problem worldwide. As of August 2020, it has affected more than 18 million humans and …

Tackling the COVID-19 “cytokine storm” with microRNA mimics directly targeting the 3'UTR of pro-inflammatory mRNAs

J Gasparello, A Finotti, R Gambari - Medical Hypotheses, 2021 - Elsevier
COVID-19 is characterized by two major clinical phases, the SARS-CoV-2 infection of target
cells and tissues, and a deep inflammatory state, known as “cytokine storm”, caused by …

Nucleic acid-based COVID-19 therapy targeting cytokine storms: strategies to quell the storm

MAH Abusalah, M Khalifa, MAI Al-Hatamleh… - Journal of Personalized …, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) has shaken the world and triggered drastic changes
in our lifestyle to control it. Despite the non-typical efforts, COVID-19 still thrives and plagues …

microRNAs and inflammatory immune response in SARS-CoV-2 infection: a narrative review

B Maranini, G Ciancio, M Ferracin, R Cultrera… - Life, 2022 - mdpi.com
The current SARS-CoV-2 pandemic has emerged as an international challenge with strong
medical and socioeconomic impact. The spectrum of clinical manifestations of SARS-CoV-2 …

The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection

R Mirzaei, F Mahdavi, F Badrzadeh… - International …, 2021 - Elsevier
The novel coronavirus disease 2019 (COVID-19) pandemic has imposed significant public
health problems for the human populations worldwide after the 1918 influenza A virus …

[HTML][HTML] Role of microRNAs in COVID-19 with implications for therapeutics

N Arghiani, T Nissan, MM Matin - Biomedicine & Pharmacotherapy, 2021 - Elsevier
COVID-19 is a pneumonia-like disease with highly transmittable and pathogenic properties
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which infects …

SARS-CoV-2-associated organs failure and inflammation: a focus on the role of cellular and viral microRNAs

R Rasizadeh, PS Aghbash, JS Nahand… - Virology journal, 2023 - Springer
SARS-CoV-2 has been responsible for the recent pandemic all over the world, which has
caused many complications. One of the hallmarks of SARS-CoV-2 infection is an induced …

Prediction and analysis of microRNAs involved in COVID-19 inflammatory processes associated with the NF-kB and JAK/STAT signaling pathways

Z Amini-Farsani, M Yadollahi-Farsani, S Arab… - International …, 2021 - Elsevier
COVID-19 is the cause of a pandemic associated with substantial morbidity and mortality. As
yet, there is no available approved drug to eradicate the virus. In this review article, we …

Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs

M Aslani, SS Mortazavi-Jahromi, A Mirshafiey - International …, 2021 - Elsevier
Abstract SARS-CoV-2, as the causative agent of COVID-19, is an enveloped positives-sense
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …

[HTML][HTML] Circulating microRNAs as emerging regulators of COVID-19

Y Liang, D Fang, X Gao, X Deng, N Chen, J Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …