COVID-19 and extracellular vesicles: an intriguing interplay

G Pocsfalvi, R Mammadova… - Kidney and Blood …, 2020 - karger.com
Background: The outbreak of severe acute respiratory syndrome β-coronavirus 2 (SARS-
CoV-2) has the potential to become a long-lasting global health crisis. The number of people …

Extracellular vesicle-based therapy for COVID-19: Promises, challenges and future prospects

V Karn, S Ahmed, LW Tsai, R Dubey, S Ojha, HN Singh… - Biomedicines, 2021 - mdpi.com
The COVID-19 pandemic has become a serious concern and has negatively impacted
public health and the economy. It primarily targets the lungs, causing acute respiratory …

The potential role of extracellular vesicles in COVID-19 treatment: opportunity and challenge

Y Yan, W Zhou, Y Wang, Q Guo, F Zhao… - Frontiers in Molecular …, 2021 - frontiersin.org
SARS-CoV-2 infection has become an urgent public health concern worldwide, severely
affecting our society and economy due to the long incubation time and high prevalence …

Update on extracellular vesicle-based vaccines and therapeutics to combat COVID-19

T Mustajab, MS Kwamboka, DA Choi, DW Kang… - International Journal of …, 2022 - mdpi.com
The COVID-19 pandemic has had a deep impact on people worldwide since late 2019 when
SARS-CoV-2 was first identified in Wuhan, China. In addition to its effect on public health, it …

Exploiting extracellular vesicles strategies to modulate cell death and inflammation in COVID-19

B Bortot, A Romani, G Ricci, S Biffi - Frontiers in pharmacology, 2022 - frontiersin.org
The coronavirus disease (COVID-19) is responsible for more than 5 million deaths
worldwide, with respiratory failure being the most common clinical presentation. COVID-19 …

Immunomodulatory extracellular vesicles: an alternative to cell therapy for COVID-19

A Gupta, K Shivaji, S Kadam, M Gupta… - Expert Opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction: SARS-CoV-2 induces a cytokine storm and can cause
inflammation, fibrosis and apoptosis in the lungs, leading to acute respiratory distress …

The role of extracellular vesicles in COVID-19 virus infection

M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …

Shedding lights on the extracellular vesicles as functional mediator and therapeutic decoy for COVID-19

A Thakur - Life, 2023 - mdpi.com
COVID-19 is an infectious disease caused by the novel coronavirus (SARS-CoV-2) that first
appeared in late 2019 and has since spread across the world. It is characterized by …

Application of stem cell-derived extracellular vesicles as an innovative theranostics in microbial diseases

H Keshavarz Alikhani, B Shokoohian… - Frontiers in …, 2021 - frontiersin.org
Extracellular vesicles (EVs), as nano-/micro-scale vehicles, are membranous particles
containing various cargoes including peptides, proteins, different types of RNAs and other …

A role for extracellular vesicles in SARS-CoV-2 therapeutics and prevention

J Machhi, F Shahjin, S Das, M Patel… - Journal of Neuroimmune …, 2021 - Springer
Extracellular vesicles (EVs) are the common designation for ectosomes, microparticles and
microvesicles serving dominant roles in intercellular communication. Both viable and dying …