Mesenchymal stem cells and their derived exosomes to combat Covid–19

M Yousefi Dehbidi, N Goodarzi… - Reviews in Medical …, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is causing an ongoing
pandemic of coronavirus disease 2019 (Covid‐19). Effective therapies are required for the …

Secretory vesicles are the principal means of SARS-CoV-2 egress

S Eymieux, R Uzbekov, Y Rouillé, E Blanchard… - Cells, 2021 - mdpi.com
The mechanisms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) egress,
similar to those of other coronaviruses, remain poorly understood. The virus buds in …

Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumonia

A Akbari, J Rezaie - Stem cell research & therapy, 2020 - Springer
Background The outbreak of a new virus known as severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has now become the main health concern all over the world …

[HTML][HTML] Mesenchymal stem cells and their extracellular vesicles: a potential game changer for the COVID-19 crisis

DH Kassem, MM Kamal - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Corona virus disease 2019 (COVID-19) is a global public health crisis. The high infectivity of
the disease even from non-symptomatic infected patients, together with the lack of a …

Circulatory exosomes from COVID-19 patients trigger NLRP3 inflammasome in endothelial cells

S Sur, R Steele, TS Isbell, R Ray, RB Ray - Mbio, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces
inflammatory response, cytokine storm, venous thromboembolism, coagulopathy, and …

Mesenchymal stem cell derived-exosomes as effective factors in reducing cytokine storm symptoms of COVID-19

AH Kheirkhah, SH Shahcheraghi… - Protein and Peptide …, 2021 - ingentaconnect.com
Given that conventional therapies are ineffective for COVID-19, obtained exosomes from
stem cells have been proposed as a sustainable and effective treatment. Exosomes are …

Mesenchymal stem cells and exosome therapy for COVID-19: current status and future perspective

A Gupta, S Kashte, M Gupta, HC Rodriguez… - Human cell, 2020 - Springer
Acute respiratory distress syndrome (ARDS) is the main cause for the COVID-19 infection-
related morbidity and mortality. Recent clinical evidences suggest increased level of …

Systematic review of extracellular vesicle‐based treatments for lung injury: are EVs a potential therapy for COVID‐19?

K Khalaj, RL Figueira, L Antounians… - Journal of …, 2020 - Wiley Online Library
Severe COVID‐19 infection results in bilateral interstitial pneumonia, often leading to acute
respiratory distress syndrome (ARDS) and pulmonary fibrosis in survivors. Most patients with …

Could Mesenchymal stem cell-derived exosomes be a therapeutic option for critically ill COVID-19 patients?

C Gardin, L Ferroni, JC Chachques… - Journal of Clinical …, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan,
China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 …

Extracellular vesicle associated miRNAs regulate signaling pathways involved in COVID-19 pneumonia and the progression to severe acute respiratory corona virus …

AS Meidert, S Hermann, F Brandes, B Kirchner… - Frontiers in …, 2021 - frontiersin.org
Background Extracellular vesicles (EVs) are mediators of cell-to-cell communication in
inflammatory lung diseases. They function as carriers for miRNAs which regulate mRNA …