H Shegarfi, F Naddafi… - The Scientific World …, 2012 - Wiley Online Library
Rheumatoid arthritis (RA) is a long‐term disease that leads to inflammation of the joints and surrounding tissues. Natural killer (NK) cells are an important part of the innate immune …
LA Fogel, WM Yokoyama, AR French - Arthritis research & therapy, 2013 - Springer
Natural killer (NK) cells are innate lymphocytes that play a critical role in early host defense against viruses. Through their cytolytic capacity and generation of cytokines and …
AR French, WM Yokoyama - Arthritis Res Ther, 2003 - Springer
Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage …
Although natural killer (NK) cells have been implicated in regulating immune responses, their ability to modulate disease development in autoimmune arthritis has not been …
K Coppieters, P Dewint, K Van Beneden… - …, 2007 - academic.oup.com
The importance of T cell participation in the aetiology and pathogenesis of rheumatoid arthritis (RA) is now widely appreciated. The disease is mediated by activated pro …
CT De Matos, L Berg, J Michaëlsson… - …, 2007 - Wiley Online Library
Natural killer (NK) cells are activated early during inflammatory events and contribute to the shaping of the ensuing adaptive immune response. To further understand the role for NK …
C Pridgeon, GP Lennon, L Pazmany… - …, 2003 - academic.oup.com
Background. Natural killer (NK) cells play an important role in several animal models of autoimmunity by modulating T‐cell responses, but it is unclear whether human NK cells …
Objective Natural killer (NK) cells are part of the innate immune system which not only provides a primary response to pathogenic conditions but can also play an important …
Natural killer (NK) cells are a specialised population of innate lymphoid cells (ILCs) that help control local immune responses. Through natural cytotoxicity, production of cytokines and …