Abstract Interleukin‐10 (IL‐10) exerts a wide spectrum of regulatory activities in the immune
and inflammatory response. The aim of this study was to investigate the role of endogenous …

Interleukin-10 (IL-10) has been utilized as a neuroprotective agent in experimental models
of spinal cord injury because of its potent anti-inflammatory properties. Previous studies …

Following the initial impact, spinal cord injury (SCI) triggers a number of inflammatory
responses which can exacerbate tissue damage in the cord and impair functional recovery …

Background Recent in vivo and in vitro studies in non-neuronal and neuronal tissues have
shown that different pathways of macrophage activation result in cells with different …

Traumatic spinal cord injury (SCI) triggers inflammatory reactions in which various types of
cells and cytokines are involved. Several proinflammatory cytokines are up‐regulated after …

In these studies, we examined the neuroprotective effects of the potent antiinflammatory
cytokine interleukin-10 (IL-10) following spinal cord injury (SCI). Neuroprotection was …

Abstract Interleukin-6 (IL)-6 was originally discovered as a factor that contributes to the
secondary pathological and inflammatory response in the central nervous system (CNS) …

We have previously reported that the transplantation of dendritic cells (DCs) brings about
functional recovery after spinal cord injury in mice through the activation of endogenous …

Background Spinal cord injury (SCI) is a devastating condition with substantial functional
and social morbidity. Previous research has established that the neuroinflammatory …

The release of inflammatory mediators from immune and glial cells either in the peripheral or
CNS may have an important role in the development of physiopathological processes such …