Parkinson's disease is one of the most common neurodegenerative diseases caused by the
loss of dopaminergic neurons in the substantia nigra pars compacta. Pharmacological …

Ineffective therapeutic treatments and inadequate repair ability in the central nervous system
are disturbing problems for several neurological diseases. Fortunately, the development of …

Abstract Parkinson's disease (PD), one of the most frequent neurodegenerative disorders, is
primarily caused by the selective degeneration of specific neuronal populations, particularly …

Parkinson's disease (PD) is the most common movement disorder. The neuropathology is
characterized by the loss of dopamine neurons in the substantia nigra pars compacta …

Cell transplant therapy for Parkinson's disease (PD) has been in use for over 2 decades as
an experimental treatment. Different cell types have been proposed as better therapeutic …

Clinical studies with intrastriatal transplants of human embryonic mesencephalic tissue have
provided proof-of-principle for the cell replacement strategy in Parkinson's disease (PD) …

Parkinson's disease (PD) is a neurodegenerative disorder caused by the loss of neurons in
the substantia nigra pars compacta and a striatal deficiency of dopamine. PD typically affects …

Parkinson's disease is the second most common form of neurodegeneration, and it poses a
major threat to the quality of life of older adults. Stem cell transplantation, which has attracted …

Stem cells offer great promise as a therapy for Parkinson's disease, but numerous hurdles
remain to be overcome with stem cell therapy. The adverse event profile of transplantation …

Motor dysfunctions in Parkinson's disease are considered to be primarily due to the
degeneration of dopaminergic neurons in the substantia nigra pars compacta …