BACKGROUND: Gene× environment (G× E) interactions are known to predict susceptibility
to disorders such as depression and anxiety. Adverse experiences in childhood and number …

BackgroundAdverse childhood experiences have been described as one of the major
environmental risk factors for depressive disorder. Similarly, the deleterious impact of early …

There is a strong etiological link between brain‐derived neurotrophic factor and depression,
but the neurocellular mechanisms and gene–environment interactions remain obscure. This …

Etiological research has indicated the gene–environment interaction (G× E) on adolescent
anxiety. This study aimed to examine how the BDNF Val66Met polymorphism interacted with …

Kaufman et al.[2006] reported a higher order interaction effect between specific genetic and
environmental factors in a model of depressive symptoms, requiring independent …

Depressive symptoms are prevalent and rise during adolescence. The present study is a
prospective investigation of environmental and genetic factors that contribute to the growth …

Background The interplay among lifetime adversities and the genetic background has been
previously examined on a variety of measures of depression; however, only few studies …

Background: There is limited evidence for a moderating role of both serotonin transporter
(SERT) and brain-derived neurotrophic factor (BDNF) genes on the risk for major depression …

The brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism and life stress
have been associated with negative emotionality (eg, neuroticism), but relevant evidence is …

Although depressive symptoms are common during adolescence, little research has
examined gene–environment interaction on youth depression. This study chose the brain …