The advent of the cytokine storm

IA Clark - Immunology and cell biology, 2007 - search.proquest.com
The term 'cytokine storm'is now used in popular culture as an explanation for the distinctly
unpleasant feeling we all sense at the onset of flu. The expression certainly has common …

The meteorology of cytokine storms, and the clinical usefulness of this knowledge

IA Clark, B Vissel - Seminars in immunopathology, 2017 - Springer
The term cytokine storm has become a popular descriptor of the dramatic harmful
consequences of the rapid release of polypeptide mediators, or cytokines, that generate …

The pathophysiology of acute graft‐versus‐host disease

M Jaksch, J Mattsson - Scandinavian journal of immunology, 2005 - Wiley Online Library
Despite improvements in allogeneic stem cell transplantation, acute graft‐versus‐host
disease (GVHD) remains a significant problem after transplantation, and it is still a major …

Clinical “cytokine storm” as revealed by monocyte intracellular flow cytometry: correlation of tumor necrosis factor α with severe gut graft-versus-host disease

DH Fowler, J Foley, JW Hou, J Odom, K Castro… - Clinical …, 2004 - Elsevier
Background & Aims: Gut graft-versus-host disease (GVHD) contributes significantly to
lethality after allogeneic hematopoietic stem-cell transplantation (HSCT). In murine models …

Immunobiology of acute graft-versus-host disease

P Reddy, JLM Ferrara - Blood reviews, 2003 - Elsevier
Graft-versus-host disease (GVHD) has been the primary limitation to the wider application of
allogeneic bone marrow transplantation (BMT). The immunobiology of acute GVHD is …

Cytokine storms in infectious diseases

JR Teijaro - Seminars in immunopathology, 2017 - Springer
The term Bcytokine storm^ has been adopted in the past several decades as a phrase to
describe the aberrant production of soluble mediators and the accompanying …

Pathophysiology of acute graft‐versus‐host disease

P Reddy - Hematological oncology, 2003 - Wiley Online Library
Graft‐versus‐host disease (GVHD) has been the primary limitation to the wider application
of allogeneic bone marrow transplantation (BMT). The pathophysiology of acute GVHD is …

The pathophysiology of acute graft-versus-host disease

JLM Ferrara, KR Cooke, T Teshima - International journal of hematology, 2003 - Springer
The pathophysiology of acute graft-versus-host disease (GVHD) is a complex process that
can be conceptualized in three phases. In the first phase, high-dose chemoradiotherapy …

Microbial/host interactions in health and disease: who controls the cytokine network?

B Henderson, S Poole, M Wilson - Immunopharmacology, 1996 - Elsevier
The interacting cellular and molecular systems which we classify as immunity and
inflammation evolved to protect the organism from exogenous parasites including viruses …

Cytokine dysregulation as a mechanism of graft versus host disease

JLM Ferrara - Current opinion in immunology, 1993 - Elsevier
Graft versus host disease (GVHD) remains the major complication of allogeneic bone
marrow transplantation. T cells in the donor bone marrow recognize and react against host …