A metal-free hydroxyalkylation-initiated radical six-membered heterocycle formation reaction
of N-allylbenzamide is developed. This reaction proceeds through C (sp3)–H bond …

An oxidative reaction for the synthesis of 4-alkyl-substituted dihydroisoquinolin-1 (2H)-ones
with N-allylbenzamide derivatives as starting materials has been developed. The radical …

An efficient metal-free and practical method for the synthesis of disubstituted dihydroquinolin-
2 (1H)-ones via intermolecular radical tandem addition/cyclization was developed. This …

In this work, switchable synthesis of isoquinolin-1-one and 3-hydroxylisoquinolin-1, 4-dione
from 2-alkynylbenzamide is reported. The transformation works well with good yields and a …

DBU-Promoted Cyclization of ortho-(3-Hydroxy-1-alkynyl)benzamide: Synthesis of trans-3,4-Dihydroisoquinolin-1(2H)-ones
and (E)-4-(1-Alkenyl)isoquinolin-1(2H)-ones | The Journal of Organic Chemistry ACS ACS …

3, 4-Dihydroquinolin-2-ones are of great importance in the areas of pharmaceuticals.
However, the direct intramolecular radical cyclizations of the corresponding amide …

A metal-free alkyl radical induced addition/cyclization reaction of acrylamide has been
developed. The process involved C (sp3)–H bond cleavage, alkylation of the double bond …

A novel synthesis of sulfonated dihydroisoquinolinones via cascade radical addition and
cyclization was developed in the presence of tert-butyl hydroperoxide (TBHP). The reactions …

We report a convenient process for synthesizing indolo-[2, 1-a] isoquinoline tetracyclic
skeletons in one pot via a low-cost copper-catalyzed tandem amino radical cyclization, in …

Herein, a novel and efficient intermolecular cyclization of 2-aminoacetophenones with
aldehydes was developed for the synthesis of 2-aryl-4-quinolones through C–C and C–N …