Episodic memories are stored in distributed neurons but how eligibility of individual neurons
to coding ensembles is determined remains elusive. We identified thousands of …

Sensory inputs activate sparse neuronal ensembles in the dentate gyrus of the
hippocampus, but how eligibility of individual neurons to recruitment is determined remains …

Epigenetic and associated gene expression changes in the brain drive animals' ability to
adapt to changing environments. However, epigenetic attributes of environmental …

Epigenetic mechanisms including altered DNA methylation are critical for altered gene
transcription subserving synaptic plasticity and the retention of learned behavior. Here, we …

The epigenome and three-dimensional (3D) genomic architecture are emerging as key
factors in the dynamic regulation of different transcriptional programs required for neuronal …

Although long-lasting behavioral memories have long been thought to require equally
persistent molecular changes, little is known about the biochemical underpinnings of …

In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …

The long-term stabilization of memory traces or engram involves the rapid formation of
cortical engrams during encoding that mature functionally over time guided by the activity of …

Although the term 'epigenetics 'was coined nearly seventy years ago, its critical function in
memory processing by the adult CNS has only recently been appreciated. The hypothesis …

Neuronal diversity is essential for mammalian brain function but poses a challenge to
molecular profiling. To address the need for tools that facilitate cell-type-specific epigenomic …