The COVID-19 inflammation and high mortality mechanism trigger

S Stróż, P Kosiorek, A Stasiak-Barmuta - Immunogenetics, 2024 - Springer
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) lasted from March 2020 to May 2023, infecting over 689 million and causing …

SARS-CoV-2 infection and the antiviral innate immune response

H Yang, Y Lyu, F Hou - Journal of Molecular Cell Biology, 2020 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak began in
December 2019, causing the illness known as the novel coronavirus disease 2019 (COVID …

A scoping review of the pathophysiology of COVID-19

PE Marik, J Iglesias, J Varon… - International journal of …, 2021 - journals.sagepub.com
COVID-19 is a highly heterogeneous and complex medical disorder; indeed, severe COVID-
19 is probably amongst the most complex of medical conditions known to medical science …

Mechanistic insight into the protective and pathogenic immune-responses against SARS-CoV-2

PK Purbey, K Roy, S Gupta, MK Paul - Molecular Immunology, 2023 - Elsevier
COVID-19 is a severe respiratory illness that has emerged as a devasting health problem
worldwide. The disease outcome is heterogeneous, which is most likely dependent on the …

Immune-profiling of SARS-CoV-2 viremic patients reveals dysregulated innate immune responses

X Sun, C Gao, K Zhao, Y Yang, Y Rassadkina… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 plasma viremia has been associated with severe disease and death in COVID-
19. However, the effects of viremia on immune responses in blood cells remain unclear. The …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

Immunologic aspects of characteristics, diagnosis, and treatment of coronavirus disease 2019 (COVID-19)

FY Chang, HC Chen, PJ Chen, MS Ho… - Journal of biomedical …, 2020 - Springer
Abstract On March 11, 2020, the World Health Organization declared the worldwide spread
of the infectious disease COVID-19, caused by a new strain of coronavirus, SARS-CoV-2, as …

A contemporary review on pathogenesis and immunity of COVID-19 infection

R Mirzaei, S Karampoor, M Sholeh, P Moradi… - Molecular biology …, 2020 - Springer
Emerging of the COVID-19 pandemic has raised interests in the field of biology and
pathogenesis of coronaviruses; including interactions between host immune reactions …

The interplay between dendritic cells and CD8 T lymphocytes is a crucial component of SARS-CoV-2 immunity

J Buttenschön, J Mattner - Cellular & Molecular Immunology, 2021 - nature.com
SARS-CoV-2, a novel beta-coronavirus (CoV), causes the coronavirus disease 2019
(COVID-19) pandemic, which manifests with a wide clinical spectrum ranging from …

[HTML][HTML] From cell to symptoms: The role of SARS-CoV-2 cytopathic effects in the pathogenesis of COVID-19 and long COVID

P Gonzalez-Garcia, O Fiorillo Moreno… - International Journal of …, 2023 - mdpi.com
Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection triggers various
events from molecular to tissue level, which in turn is given by the intrinsic characteristics of …