Optical mapping of genomic DNA is of relevance for a plethora of applications such as
scaffolding for sequencing and detection of structural variations as well as identification of …

Optical DNA mapping (ODM) allows visualization of long-range sequence information along
single DNA molecules. The data can for example be used for detecting long range structural …

We demonstrate a single DNA molecule optical mapping assay able to resolve a specific
Escherichia coli strain from other strains. The assay is based on competitive binding of the …

Next generation sequencing (NGS) is revolutionizing all fields of biological research but it
fails to extract the full range of information associated with genetic material. Optical mapping …

Optical DNA mapping has over the last decade emerged as a very powerful tool for
obtaining long range sequence information from single DNA molecules. In optical DNA …

DNA mapping is an important analytical tool in genomic sequencing, medical diagnostics
and pathogen identification. Here we report an optical DNA mapping strategy based on …

The human genome contains multiple layers of information that extend beyond the genetic
sequence. In fact, identical genetics do not necessarily yield identical phenotypes as evident …

The technologies associated with DNA sequencing are rapidly evolving. Indeed, single‐
molecule DNA sequencing strategies are cheaper and faster than ever before. Despite this …

Optical mapping of DNA provides large-scale genomic information that can be used to
assemble contigs from next-generation sequencing, and to detect rearrangements between …

Rapid, multiplexed, sensitive and specific molecular detection is of great demand in gene
profiling, drug screening, clinical diagnostics and environmental analysis,,. One of the major …