Whereas all of the integrins in the VLA protein subfamily are involved in cell‐extracellular
matrix interactions, only VLA‐4 (through the α4 subunit) has been implicated in the …

The VLA-4 (CD49d/CD29) integrin is the only member of the VLA family expressed by
resting lymphoid cells that has been involved in cell-cell adhesive interactions. We here …

ABSTRACT Various β1 integrins (VLA-2, VLA-3, VLA-4) have been suggested to bind
directly to themselves or to each other, thus mediating cell-cell adhesion. Here we …

The human integrin VLA (very late activation antigens)-4 (CD49d/CD29), the leukocyte
receptor for both the CS-1 region of plasma fibronectin (Fn) and the vascular cell surface …

The VLA-4 (α4β1) integrin is involved in the adhesion of cells to fibronectin and vascular cell
adhesion molecule-1 (VCAM-1). In order to study α4 structure-function relationships, we …

We have expressed the β1B integrin subunit in β1-deficient GD25 cells to examine β1B
functions without the interference of endogenous β1A expression. As previously reported …

α 4 β 1 integrin (VLA-4) appears to be unique among the leukocyte integrins in that it can
initiate the adhesion of circulating lymphocytes without cellular activation. It is not known …

Integrins can exist in a range of functional states, depending on the cell type and its state of
activation. Although the mechanism that controls activity is unknown, it has been suggested …

To assess directly the functional role of the integrin VLA-3 (alpha 3 beta 1), we transfected
human alpha 3 cDNA into erythroleukemia (K562) cells and rhabdomyosarcoma (RD) cells …

The involvement of the VLA-4 integrin in an alternative leukocyte homotypic adhesion
mechanism that is LFA-1/ICAM-1 independent, has been previously reported. We describe …