Four pleiotropic loci associated with fat mass and lean mass

Y Liu, S Ran, Y Lin, YX Zhang, XL Yang… - International Journal of …, 2020 - nature.com
Background Fat mass and lean mass are two biggest components of body mass. Both fat
mass and lean mass are under strong genetic determinants and are correlated. Methods We …

[HTML][HTML] Disentangling the genetics of lean mass

D Karasik, MC Zillikens, YH Hsu, A Aghdassi… - The American journal of …, 2019 - Elsevier
Background Lean body mass (LM) plays an important role in mobility and metabolic
function. We previously identified five loci associated with LM adjusted for fat mass in …

Genome-wide association study identifies genetic risk loci for adiposity in a Taiwanese population

HSC Wong, SY Tsai, HW Chu, MR Lin, GH Lin… - PLoS …, 2022 - journals.plos.org
Overweight and obese are risk factors for various diseases. In Taiwan, the combined
prevalence of overweight and obesity has increased dramatically. Here, we conducted a …

[PDF][PDF] Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

N Genet - Nat Genet, 2010 - academia.edu
Users may view, print, copy, download and text and data-mine the content in such
documents, for the purposes of academic research, subject always to the full Conditions of …

Correction: Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution

CM Lindgren, IM Heid, JC Randall, C Lamina… - PLoS …, 2009 - cdr.lib.unc.edu
To identify genetic loci influencing central obesity and fat distribution, we performed a meta-
analysis of 16 genome-wide association studies (GWAS, N= 38,580) informative for adult …

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

CM Lindgren, IM Heid, JC Randall, C Lamina… - PLoS …, 2009 - journals.plos.org
To identify genetic loci influencing central obesity and fat distribution, we performed a meta-
analysis of 16 genome-wide association studies (GWAS, N= 38,580) informative for adult …

[HTML][HTML] Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

MC Zillikens, S Demissie, YH Hsu… - Nature …, 2017 - nature.com
Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We
performed a genome-wide association study for whole body (20 cohorts of European …

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi… - Nature …, 2011 - nature.com
In the version of this article initially published, there were errors in Table 1. Specifically, for
eight SNPs, the effect allele frequencies were reversed. The correct effect allele frequencies …

Gene-based genome-wide association study identified 19p13. 3 for lean body mass

S Ran, L Zhang, L Liu, AP Feng, YF Pei, L Zhang… - Scientific Reports, 2017 - nature.com
Lean body mass (LBM) is a complex trait for human health. To identify genomic loci
underlying LBM, we performed a gene-based genome-wide association study of lean mass …

Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity

YF Pei, L Zhang, Y Liu, J Li, H Shen… - Human molecular …, 2014 - academic.oup.com
Obesity is a major public health problem with strong genetic determination. Multiple genetic
variants have been implicated for obesity by conducting genome-wide association (GWA) …