Pathogenetic profiling of COVID-19 and SARS-like viruses

Z Nain, HK Rana, P Liò, SMS Islam… - Briefings in …, 2021 - academic.oup.com
Abstract The novel coronavirus (2019-nCoV) has recently emerged, causing COVID-19
outbreaks and significant societal/global disruption. Importantly, COVID-19 infection …

Novel signaling pathways regulate SARS-CoV and SARS-CoV-2 infectious disease

LC Cheng, TJ Kao, NN Phan, CC Chiao, MC Yen… - Medicine, 2021 - journals.lww.com
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 induces severe infection,
and it is responsible for a worldwide disease outbreak starting in late 2019. Currently, there …

Structural genomics of SARS-CoV-2 indicates evolutionary conserved functional regions of viral proteins

S Srinivasan, H Cui, Z Gao, M Liu, S Lu, W Mkandawire… - Viruses, 2020 - mdpi.com
During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-
CoV-2, has already infected over one-hundred thousand people worldwide and has taken …

[HTML][HTML] Transcriptomic signatures and repurposing drugs for COVID-19 patients: findings of bioinformatics analyses

G Li, S Ruan, X Zhao, Q Liu, Y Dou, F Mao - Computational and Structural …, 2021 - Elsevier
The novel coronavirus SARS-CoV-2 is damaging the world's social and economic fabrics
seriously. Effective drugs are urgently needed to decrease the high mortality rate of COVID …

The global landscape of SARS-CoV-2 genomes, variants, and haplotypes in 2019nCoVR

S Song, L Ma, D Zou, D Tian, C Li, J Zhu… - Genomics …, 2020 - academic.oup.com
Abstract On January 22, 2020, China National Center for Bioinformation (CNCB) released
the 2019 Novel Coronavirus Resource (2019nCoVR), an open-access information resource …

Transcriptomic studies revealed pathophysiological impact of COVID-19 to predominant health conditions

Z Nain, SK Barman, MM Sheam, SB Syed… - Briefings in …, 2021 - academic.oup.com
Despite the association of prevalent health conditions with coronavirus disease 2019
(COVID-19) severity, the disease-modifying biomolecules and their pathogenetic …

COVID-19 outbreak: an overview

M Ciotti, S Angeletti, M Minieri, M Giovannetti… - Chemotherapy, 2020 - karger.com
Abstract Background: In late December 2019, Chinese health authorities reported an
outbreak of pneumonia of unknown origin in Wuhan, Hubei Province. Summary: A few days …

Bioinformatics analyses of significant genes, related pathways, and candidate diagnostic biomarkers and molecular targets in SARS-CoV-2/COVID-19

B Vastrad, C Vastrad, A Tengli - Gene Reports, 2020 - Elsevier
Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection is a leading
cause of pneumonia and death. The aim of this investigation is to identify the key genes in …

Understanding genomic diversity, pan-genome, and evolution of SARS-CoV-2

A Parlikar, K Kalia, S Sinha, S Patnaik, N Sharma… - PeerJ, 2020 - peerj.com
Coronovirus disease 2019 (COVID-19) infection, which originated from Wuhan, China, has
seized the whole world in its grasp and created a huge pandemic situation before humanity …

Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis

MG Ferrarini, A Lal, R Rebollo, AJ Gruber… - Communications …, 2021 - nature.com
The novel betacoronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
caused a worldwide pandemic (COVID-19) after emerging in Wuhan, China. Here we …