Helicobacter pylori Outer Membrane Vesicle Size Determines Their Mechanisms of Host Cell Entry and Protein Content

L Turner, NJ Bitto, DL Steer, C Lo, K D'Costa… - Frontiers in …, 2018 - frontiersin.org
Gram-negative pathogens ubiquitously shed outer membrane vesicles (OMVs) that play a
central role in initiating and regulating pathogenesis in the host. Due to their highly …

Helicobacter pylori Growth Stage Determines the Size, Protein Composition, and Preferential Cargo Packaging of Outer Membrane Vesicles

L Zavan, NJ Bitto, EL Johnston, DW Greening… - …, 2019 - Wiley Online Library
Gram‐negative bacteria release outer membrane vesicles (OMVs) as part of their normal
growth that contain a range of cargo from their parent bacterium, including DNA, RNA, and …

Uptake of Helicobacter pylori vesicles is facilitated by clathrin-dependent and clathrin-independent endocytic pathways

A Olofsson, L Nygård Skalman, I Obi, R Lundmark… - MBio, 2014 - Am Soc Microbiol
Bacteria shed a diverse set of outer membrane vesicles that function as transport vehicles to
deliver effector molecules and virulence factors to host cells. Helicobacter pylori is a gastric …

Helicobacter pylori-Derived Outer Membrane Vesicles (OMVs): Role in Bacterial Pathogenesis?

M Jarzab, G Posselt, N Meisner-Kober, S Wessler - Microorganisms, 2020 - mdpi.com
Persistent infections with the human pathogen Helicobacter pylori (H. pylori) have been
closely associated with the induction and progression of a wide range of gastric disorders …

Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori

E Mullaney, PA Brown, SM Smith… - PROTEOMICS …, 2009 - Wiley Online Library
The gastric pathogen Helicobacter pylori causes a spectrum of gastro‐duodenal diseases,
which may be mediated in part by the outer membrane vesicles (OMVs) constitutively shed …

Helicobacter pylori Outer Membrane Vesicles Modulate Proliferation and Interleukin-8 Production by Gastric Epithelial Cells

S Ismail, MB Hampton, JI Keenan - Infection and immunity, 2003 - Am Soc Microbiol
Helicobacter pylori infection, which is always associated with gastritis, can progress to
ulceration or malignancy. The diversity in clinical outcomes is partly attributed to the …

Helicobacter pylori Outer Membrane Vesicles and Extracellular Vesicles from Helicobacter pylori-Infected Cells in Gastric Disease Development

MF González, P Díaz, A Sandoval-Bórquez… - International Journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are cell-derived vesicles important in intercellular
communication that play an essential role in host-pathogen interactions, spreading …

Outer membrane vesicles of Vibrio cholerae protect and deliver active cholera toxin to host cells via porin-dependent uptake

FG Zingl, HB Thapa, M Scharf, P Kohl, AM Müller… - MBio, 2021 - Am Soc Microbiol
Outer membrane vesicles (OMVs) are an emerging research field due to their multifactorial
composition and involvement in interspecies and intraspecies communication. Recent …

Orally-administered outer-membrane vesicles from Helicobacter pylori reduce H. pylori infection via Th2-biased immune responses in mice

Q Liu, X Li, Y Zhang, Z Song, R Li, H Ruan… - Pathogens and …, 2019 - academic.oup.com
As the trend of antibiotic resistance has increased, prevention and treatment of Helicobacter
pylori infection have been challenged by the fact that no vaccines preventing H. pylori …

Increased Outer Membrane Vesicle Formation in a Helicobacter pylori tolB Mutant

L Turner, J Praszkier, ML Hutton, D Steer… - …, 2015 - Wiley Online Library
Background Multiple studies have established the importance of the tol‐pal gene cluster in
bacterial cell membrane integrity and outer membrane vesicle (OMV) formation in …