Highlights•Microbes are engineered to diagnose and treat many disorders and
diseases.•Biosensors improve the control of microbes engineered for medical …

Engineered microbes are exciting alternatives to current diagnostics and therapeutics.
Researchers have developed a wide range of genetic tools and parts to engineer probiotic …

Microbes can be engineered to act like living therapeutics designed to perform specific
actions in the human body. From fighting and preventing infections to eliminating tumors and …

Synthetic biology offers new tools and capabilities of engineering cells with desired
functions for example as new biosensing platforms leveraging engineered microbes. In the …

The ability to detect disease early and deliver precision therapy would be transformative for
the treatment of human illnesses. To achieve these goals, biosensors that can pinpoint when …

Sensitive and minimally invasive medical diagnostics are essential to the early detection of
diseases, monitoring their progression and response to treatment. Engineered bacteria as …

The engineering of microbial cells to produce and secrete therapeutics directly in the human
body, known as advanced microbial therapeutics, is an exciting alternative to current drug …

Living cells have evolved to detect and process various signals and can self‐replicate,
presenting an attractive platform for engineering scalable and affordable biosensing …

Recent advances in synthetic biology and biological system engineering have allowed the
design and construction of engineered live biotherapeutics targeting a range of human …

A complex interplay of metabolic and immunological mechanisms underlies many diseases
that represent a substantial unmet medical need. There is an increasing appreciation of the …