[HTML][HTML] Analytical validation of the Immunoscore and its associated prognostic value in patients with colon cancer

F Marliot, X Chen, A Kirilovsky, T Sbarrato… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background New and fully validated tests need to be brought into clinical practice to improve
the estimation of recurrence risk in patients with colon cancer. The aim of this study was to …

Rational bases for the use of the Immunoscore in routine clinical settings as a prognostic and predictive biomarker in cancer patients

A Kirilovsky, F Marliot, C El Sissy… - International …, 2016 - academic.oup.com
Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) tumor, nodes, metastasis (TNM) classification system based on tumor features …

Usefulness and robustness of Immunoscore for personalized management of cancer patients

F Marliot, F Pagès, J Galon - Oncoimmunology, 2020 - Taylor & Francis
This review details the analytical performance characteristics of the consensus
Immunoscore, measuring the immune response to cancer, improving the estimation of risk of …

Multicenter international society for immunotherapy of cancer study of the consensus immunoscore for the prediction of survival and response to chemotherapy in …

B Mlecnik, C Bifulco, G Bindea, F Marliot… - Journal of clinical …, 2020 - ascopubs.org
PURPOSE The purpose of this study was to evaluate the prognostic value of Immunoscore
in patients with stage III colon cancer (CC) and to analyze its association with the effect of …

The prognostic value of immunoscore in patients with colorectal cancer: A systematic review and meta‐analysis

G Sun, X Dong, X Tang, H Qu, H Zhang… - Cancer …, 2019 - Wiley Online Library
The tumor immune infiltrate, as recently evaluated with the immunoscore methodology, has
been reported to be related to colorectal cancer (CRC) progression. Nevertheless, results …

Validation of the Immunoscore (IM) as a prognostic marker in stage I/II/III colon cancer: Results of a worldwide consortium-based analysis of 1,336 patients.

J Galon, B Mlecnik, F Marliot, FS Ou, CB Bifulco… - 2016 - ascopubs.org
3500 Background: Mounting evidence indicates an enhanced lymphocytic reaction as an
informative prognostic indicator in colon cancer (CC). The IM methodology has been defined …

Therapeutic implications of the immunoscore in patients with colorectal cancer

C El Sissy, A Kirilovsky, G Zeitoun, F Marliot… - Cancers, 2021 - mdpi.com
Simple Summary Beyond the TNM-staging system, biomarkers are needed to guide cancer
treatments. We provide an overview of the Immunoscore, a standardized immune assay …

Immunoscore assay for the immune classification of solid tumors: Technical aspects, improvements and clinical perspectives

F Marliot, L Lafontaine, J Galon - Methods in Enzymology, 2020 - Elsevier
The past two decades witnessed the appreciation of the importance of specific tumor-
infiltrating immune cells in influencing tumor evolution. The discovery that a favorable …

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou… - The Lancet, 2018 - thelancet.com
Background The estimation of risk of recurrence for patients with colon carcinoma must be
improved. A robust immune score quantification is needed to introduce immune parameters …

The prognostic value of Immunoscore in patients with cancer: A pooled analysis of 10,328 patients

X Zhang, J Yang, L Du, Y Zhou… - The International Journal …, 2020 - journals.sagepub.com
Objectives: Over the past decade, some publications have reported that Immunoscore was
associated with the prognosis of several cancers. To better understand this issue, we …