Objective: High comorbidity among psychiatric disorders suggests that they may share underlying neurobiological deficits. Abnormalities in cortical thickness and volume have …
M Jalbrzikowski, D Freedman, CE Hegarty… - Journal of the American …, 2019 - Elsevier
Objective Adults with established diagnoses of serious mental illness (bipolar disorder and schizophrenia) exhibit structural brain abnormalities, yet less is known about how such …
Background This study aimed to investigate whether dimensional constructs of psychopathology relate to variation in patterns of brain development and to determine …
Childhood is an important time for the manifestation of psychopathology. Psychopathology is characterized by considerable comorbidity which is mirrored in the underlying neural …
Objective A general psychopathology (p) factor captures shared variation across mental disorders. Structural neural alterations have been associated with the p factor concurrently …
The advent of magnetic resonance imaging, which safely allows in vivo quantification of anatomical and physiological features of the brain, has revolutionized pediatric …
Objective In both children and adults, psychiatric illness is associated with structural brain alterations, particularly in the prefrontal cortex (PFC). However, most studies compare gray …
MN Pavuluri, JA Sweeney - Journal of the American Academy of Child & …, 2008 - Elsevier
OBJECTIVE: To provide an overview of clinical research aiming to develop a mechanistic understanding of brain dysfunction in child psychiatric disorders. METHOD: Technological …
Importance The trajectory of cortical gray matter development in childhood has been characterized by early neurogenesis and volume increase, peaking at puberty followed by …