Tracking brain development and dimensional psychiatric symptoms in children: a longitudinal population-based neuroimaging study

RL Muetzel, LME Blanken… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: Psychiatric symptomatology during childhood predicts persistent mental illness
later in life. While neuroimaging methodologies are routinely applied cross-sectionally to the …

Evidence for dissociable linkage of dimensions of psychopathology to brain structure in youths

AN Kaczkurkin, SS Park, A Sotiras… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: High comorbidity among psychiatric disorders suggests that they may share
underlying neurobiological deficits. Abnormalities in cortical thickness and volume have …

Structural brain alterations in youth with psychosis and bipolar spectrum symptoms

M Jalbrzikowski, D Freedman, CE Hegarty… - Journal of the American …, 2019 - Elsevier
Objective Adults with established diagnoses of serious mental illness (bipolar disorder and
schizophrenia) exhibit structural brain abnormalities, yet less is known about how such …

Brain-predicted age associates with psychopathology dimensions in youths

VL Cropley, Y Tian, K Fernando, C Pantelis… - Biological Psychiatry …, 2021 - Elsevier
Background This study aimed to investigate whether dimensional constructs of
psychopathology relate to variation in patterns of brain development and to determine …

Association of gray matter volumes with general and specific dimensions of psychopathology in children

EL Durham, HJ Jeong, TM Moore, RM Dupont… - …, 2021 - nature.com
Childhood is an important time for the manifestation of psychopathology. Psychopathology is
characterized by considerable comorbidity which is mirrored in the underlying neural …

Brain structure relations with psychopathology trajectories in the ABCD study

AL Romer, B Ren, DA Pizzagalli - Journal of the American Academy of …, 2023 - Elsevier
Objective A general psychopathology (p) factor captures shared variation across mental
disorders. Structural neural alterations have been associated with the p factor concurrently …

[HTML][HTML] Child psychiatry branch of the National Institute of Mental Health longitudinal structural magnetic resonance imaging study of human brain development

JN Giedd, A Raznahan, A Alexander-Bloch… - …, 2015 - nature.com
The advent of magnetic resonance imaging, which safely allows in vivo quantification of
anatomical and physiological features of the brain, has revolutionized pediatric …

Comparing brain morphometry across multiple childhood psychiatric disorders

AL Gold, MA Brotman, NE Adleman, SN Lever… - Journal of the American …, 2016 - Elsevier
Objective In both children and adults, psychiatric illness is associated with structural brain
alterations, particularly in the prefrontal cortex (PFC). However, most studies compare gray …

Integrating functional brain neuroimaging and developmental cognitive neuroscience in child psychiatry research

MN Pavuluri, JA Sweeney - Journal of the American Academy of Child & …, 2008 - Elsevier
OBJECTIVE: To provide an overview of clinical research aiming to develop a mechanistic
understanding of brain dysfunction in child psychiatric disorders. METHOD: Technological …

Early childhood depression and alterations in the trajectory of gray matter maturation in middle childhood and early adolescence

JL Luby, AC Belden, JJ Jackson… - JAMA …, 2016 - jamanetwork.com
Importance The trajectory of cortical gray matter development in childhood has been
characterized by early neurogenesis and volume increase, peaking at puberty followed by …