Modeling of region-specific fMRI BOLD neurovascular response functions in rat brain reveals residual differences that correlate with the differences in regional evoked …

CP Pawela, AG Hudetz, BD Ward, ML Schulte, R Li… - Neuroimage, 2008 - Elsevier
The response of the rat visual system to flashes of blue light has been studied by blood
oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI). The BOLD …

Analysis of time and space invariance of BOLD responses in the rat visual system

CJ Bailey, BG Sanganahalli, P Herman… - Cerebral …, 2013 - academic.oup.com
Neuroimaging studies of functional magnetic resonance imaging (fMRI) and
electrophysiology provide the linkage between neural activity and the blood oxygenation …

Light stimulus frequency dependence of activity in the rat visual system as studied with high-resolution BOLD fMRI

N Van Camp, M Verhoye… - Journal of …, 2006 - journals.physiology.org
The neurophysiology of the rodent visual system has mainly been investigated by invasive
and ex-vivo techniques providing fragmented data. This area of research has been deprived …

Spatial and temporal differentiation of fMRI BOLD response in primary visual cortex of human brain during sustained visual simulation

WEI Chen, XH Zhu, T Kato, P Andersen… - Magnetic resonance …, 1998 - Wiley Online Library
The blood oxygenation level dependent (BOLD) response during sustained visual
stimulation has been studied by several groups using fMRI with controversial conclusions …

Temporal dynamics of the BOLD fMRI impulse response

JA de Zwart, AC Silva, P van Gelderen, P Kellman… - Neuroimage, 2005 - Elsevier
Using computer simulations and high-resolution fMRI experiments in humans (n= 6) and rats
(n= 8), we investigated to what extent BOLD fMRI temporal resolution is limited by dispersion …

High-resolution fMRI reveals laminar differences in neurovascular coupling between positive and negative BOLD responses

J Goense, H Merkle, NK Logothetis - Neuron, 2012 - cell.com
The six cortical layers have distinct anatomical and physiological properties, like different
energy use and different feedforward and feedback connectivity. It is not known if and how …

Contribution of excitatory and inhibitory neuronal activity to BOLD fMRI

HS Moon, H Jiang, TT Vo, WB Jung… - Cerebral …, 2021 - academic.oup.com
The BOLD fMRI response in the cortex is often assumed to reflect changes in excitatory
neural activity. However, the contribution of inhibitory neurons to BOLD fMRI is unclear …

Determining excitatory and inhibitory neuronal activity from multimodal fMRI data using a generative hemodynamic model

M Havlicek, D Ivanov, A Roebroeck… - Frontiers in …, 2017 - frontiersin.org
Hemodynamic responses, in general, and the blood oxygenation level-dependent (BOLD)
fMRI signal, in particular, provide an indirect measure of neuronal activity. There is strong …

Investigating the source of BOLD nonlinearity in human visual cortex in response to paired visual stimuli

N Zhang, XH Zhu, W Chen - Neuroimage, 2008 - Elsevier
Several studies have demonstrated significant nonlinearity in the blood-oxygenation-level-
dependent (BOLD) signal. Completely understanding the nature of this nonlinear behavior is …

Hemodynamic nonlinearities affect BOLD fMRI response timing and amplitude

JA de Zwart, P van Gelderen, JM Jansma, M Fukunaga… - Neuroimage, 2009 - Elsevier
The interpretation of functional magnetic resonance imaging (fMRI) studies based on blood
oxygen-level dependent (BOLD) contrast generally relies on the assumption of a linear …