Novel 3D-printed microfluidic magnetic platform for rapid DNA isolation

G Kibar, B Sarıarslan, S Doğanay, G Yıldız… - Analytical …, 2024 - ACS Publications
This study presents a novel miniaturized device as a 3D-printed microfluidic magnetic
platform specifically designed to manipulate magnetic microparticles in a microfluidic chip …

A magnetic bead-based DNA extraction and purification microfluidic device

SM Azimi, G Nixon, J Ahern… - Microfluidics and …, 2011 - Springer
This article introduces a novel magnetic bead-based DNA extraction and purification device
using active magnetic mixing approach. Mixing and separation steps are performed using …

Magnetic Bead Chain-Based Continuous-Flow DNA Extraction for Microfluidic PCR Detection of Salmonella

Y Wang, W Qi, L Wang, J Lin, Y Liu - Micromachines, 2021 - mdpi.com
Nucleic acid extraction is crucial for PCR detection of pathogenic bacteria to ensure food
safety. In this study, a new magnetic extraction method was developed using 3D printing and …

Magnetophoretic-based microfluidic device for DNA isolation

C Hale, J Darabi - Biomicrofluidics, 2014 - pubs.aip.org
This paper presents a continuous flow microfluidic device for the separation of DNA from
blood using magnetophoresis for biological applications and analysis. This microfluidic bio …

Extraction of genomic DNA and detection of single nucleotide polymorphism genotyping utilizing an integrated magnetic bead-based microfluidic platform

KY Lien, CJ Liu, YC Lin, PL Kuo, GB Lee - Microfluidics and Nanofluidics, 2009 - Springer
This study presents a new magnetic bead-based microfluidic platform, which integrates
three major modules for rapid leukocytes purification, genomic DNA (gDNA) extraction and …

Integrated microfluidic system for efficient DNA extraction using on-disk magnetic stirrer micromixer

A Dehghan, A Gholizadeh, M Navidbakhsh… - Sensors and Actuators B …, 2022 - Elsevier
Micromixers are essential microfluidic modules for fabricating integrated lab-on-chip devices
for point-of-care applications. Ease of fabrication and integration with other fluidic modules …

Manipulation and extraction of genomic DNA from cell lysate by functionalized magnetic particles for lab on a chip applications

SW Yeung, IM Hsing - Biosensors and Bioelectronics, 2006 - Elsevier
A novel approach for extracting living cells' genomic DNA materials utilizing functionalized
magnetic particles (MPs) is reported in this investigation. This strategy is amenable to …

Continuous microfluidic purification of DNA using magnetophoresis

Y Xu, Z Zhang, Z Su, X Zhou, X Han, Q Liu - Micromachines, 2020 - mdpi.com
Automatic microfluidic purification of nucleic acid is predictable to reduce the input of original
samples and improve the throughput of library preparation for sequencing. Here, we …

Fully Integrated Microfluidic Device for Magnetic Bead Manipulation to Assist Rapid Reaction and Cleaning

Z Yang, M Ren, Y Li, M Zhou, J Peng, S Lin… - Analytical …, 2023 - ACS Publications
Methods to manipulate magnetic beads are essential factors to determine the efficiency and
dimension of an in vitro diagnostic system. Currently, using movable permanent magnets …

Rapid isolation and detection of cancer cells by utilizing integrated microfluidic systems

KY Lien, YH Chuang, LY Hung, KF Hsu, WW Lai… - Lab on a Chip, 2010 - pubs.rsc.org
The present study reports a new three-dimensional (3D) microfluidic platform capable of
rapid isolation and detection of cancer cells from a large sample volume (eg∼ 1 mL) by …