The" therapeutic misconception," described by Paul Appelbaum and colleagues more than
20 years ago, refers to the tendency of participants in clinical trials to confuse the design and …

Therapeutic misconception (TM)—when clinical research participants fail to adequately
grasp the difference between participating in a clinical trial and receiving ordinary clinical …

BY SAM HORNG AND CHRISTINE GRADY of informed consent,'which is itself fundamental
to ethical clinical research. 2 Data show that many research subjects misunderstand various …

The term therapeutic misconception was coined by Paul Appelbaum and his colleagues to
describe the tendency of patients enrolled in clinical trials to confuse research participation …

tion, it has been much discussed, and there has been no lack of data suggesting that its
prevalence is substantial. The Advisory Committee on Human Radiation Experiments …

Most ethical commentary on clinical research concerns studies involving patient-subjects.
Several reasons may account for the relative neglect of ethical appraisal of research with …

The article addresses the frequency and risk factors of therapeutic misconceptions in clinical
research. When clinical researchers fail to recognize the ways in which research …

In a recent article in The Journal of Clinical Ethics, David Wendler argues that worries about
the therapeutic misconception (TM) are not only misconceived, but detract from the larger …

To maintain a therapeutic misconception is to deny the possibility that there may be major
disadvantages to participating in clinical research that stem from the nature of the research …

Responding to the paper by Miller and Joffe, we review the development of the concept of
therapeutic misconception (TM). Our concerns about TM's impact on informed consent do …