RM Eman, HAW Meijer, FC Öner… - … Engineering Part A, 2016 - liebertpub.com
Vascularization is crucial for the induction of bone formation. In this study, we investigated the application of two subtypes of peripheral blood-derived endothelial progenitor cells …
R Zhang, Z Gao, W Geng, X Yan, F Chen… - Artificial organs, 2012 - Wiley Online Library
Tissue‐engineered bone provides a promising method for the rehabilitation of acquired bone defects and congenital deformities. However, generating a vascular supply to the …
Z Lin, X Zhang, MR Fritch, Z Li, B Kuang, PG Alexander… - Biomaterials, 2022 - Elsevier
Currently, most in vitro engineered bone tissues do not contain viable blood vessel systems, so the vascularization depends on post-implantation angiogenesis from the host, which is …
I Pennings, LA van Dijk, J van Huuksloot… - Journal of tissue …, 2019 - Wiley Online Library
To introduce a functional vascular network into tissue‐engineered bone equivalents, human endothelial colony forming cells (ECFCs) and multipotent mesenchymal stromal cells …
L Li, J Li, Q Zou, Y Zuo, B Cai, Y Li - Cell proliferation, 2019 - Wiley Online Library
Objectives The bone tissue engineering primarily focuses on three‐dimensional co‐culture systems, which physical and biological properties resemble the cell matrix of actual tissues …
FE Freeman, MG Haugh… - Tissue Engineering Part A, 2015 - liebertpub.com
Chondrogenic priming (CP) of mesenchymal stem cells (MSCs) and coculture of MSCs with human umbilical vein endothelial stem cells (HUVECs) both have been shown to …
Derivation of bone forming cells (osteoblasts) from human embryonic stem cells (hESCs) is a prerequisite for their use in clinical applications. However, there is no standard protocol for …
ZY Zhang, SH Teoh, MSK Chong, JT Schantz… - Stem …, 2009 - academic.oup.com
Mesenchymal stem cells (MSCs) from human adult bone marrow (haMSCs) represent a promising source for bone tissue engineering. However, their low frequencies and limited …
RA Kopher, VR Penchev, MS Islam, KL Hill, S Khosla… - Bone, 2010 - Elsevier
Mesenchymal stem/stromal cells (MSCs) have been isolated from various tissues and utilized for an expanding number of therapies. The developmental pathways involved in …