[HTML][HTML] An impaired inflammatory and innate immune response in COVID-19

SH Park - Molecules and cells, 2021 - Elsevier
The recent appearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has affected millions of people around the world and caused a global pandemic of …

[HTML][HTML] Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome

S Lin, Y Zhao, D Zhou, F Zhou, F Xu - Genes & Diseases, 2020 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) was first identified in China at the end of
2019. Acute respiratory distress syndrome (ARDS) represents the most common and serious …

Targeting pivotal inflammatory pathways in COVID-19: A mechanistic review

A Yarmohammadi, M Yarmohammadi, S Fakhri… - European journal of …, 2021 - Elsevier
As an emerging global health crisis, coronavirus disease 2019 (COVID-19) has been
labeled a worldwide pandemic. Growing evidence is revealing further pathophysiological …

COVID-19 and the immune response: A multi-phasic approach to the treatment of COVID-19

T Sapir, Z Averch, B Lerman, A Bodzin… - International Journal of …, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a viral agent that causes
Coronavirus disease 2019 (COVID-19), a disease that causes flu-like symptoms that, when …

Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate

P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

Cytokine storm in COVID-19: Potential therapeutics for immunomodulation

MM Rana - Journal of Research in Clinical Medicine, 2020 - library.2pressrelease.co.in
The outbreak of new coronavirus disease-20119 or COVID-19 infection has become a
global health emergency at the beginning of this year. Currently, no specific vaccines and …

The unleashing of the immune system in COVID-19 and sepsis: the calm before the storm?

S Bellinvia, CJ Edwards, M Schisano, P Banfi… - Inflammation …, 2020 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is sorely testing health care systems and …

Inflammatory pathways in COVID‐19: mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

Pharmaco-immunomodulatory interventions for averting cytokine storm-linked disease severity in SARS-CoV-2 infection

A Kumar, A Sharma, NV Tirpude, S Sharma… - …, 2022 - Springer
The year 2020 is characterised by the COVID-19 pandemic that has quelled more than half
a million lives in recent months. We are still coping with the negative repercussions of …