[HTML][HTML] Covid‐19: time for a paradigm change

FM Buonaguro, PA Ascierto, GD Morse… - Reviews in medical …, 2020 - ncbi.nlm.nih.gov
As of May 11, 2020, coronavirus disease 2019 (Covid-19) has been confirmed in 4 152 670
people worldwide, carrying a mortality of approximately 6.8%, 1 compared with a mortality …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
caused the greatest pandemic of our century. Many of the deaths related to it are due to a …

Characterisation of the pro-inflammatory cytokine signature in severe COVID-19

HC Hawerkamp, AH Dyer, ND Patil… - Frontiers in …, 2023 - frontiersin.org
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic,
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …

Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Immune Profiling of COVID-19 in Correlation with SARS and MERS

BA Khalil, SB Shakartalla, S Goel, B Madkhana… - Viruses, 2022 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a major complication of the respiratory illness
coronavirus disease 2019, with a death rate reaching up to 40%. The main underlying cause …

Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview

LM Khosroshahi, M Rokni, T Mokhtari… - International …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) infection which is caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a “public health emergency of …

COVID-19 cytokine storm: The anger of inflammation

M Mahmudpour, J Roozbeh, M Keshavarz, S Farrokhi… - Cytokine, 2020 - Elsevier
Patients with COVID-19 who require ICU admission might have the cytokine storm. It is a
state of out-of-control release of a variety of inflammatory cytokines. The molecular …

Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 9.2 million …

Immunomodulation as treatment for severe coronavirus disease 2019: a systematic review of current modalities and future directions

EA Meyerowitz, P Sen, SR Schoenfeld… - Clinical Infectious …, 2021 - academic.oup.com
In severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, viral load
peaks early and declines quickly after symptom onset. Severe coronavirus disease 2019 …

Macrophage activation syndrome and COVID-19

R Otsuka, K Seino - Inflammation and regeneration, 2020 - Springer
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating
pandemic. As we have not developed curative medicine and effective vaccine, the end of …