Anti-inflammatory and immune therapy in severe coronavirus disease 2019 (COVID-19) patients: An update

W Zhang, C Qin, Y Fei, M Shen, Y Zhou, Y Zhang… - Clinical …, 2022 - Elsevier
In March 2020, when coronavirus disease 2019 (COVID-19) was just beginning to spread
around the world, we presented the potential benefits and controversies of anti-inflammatory …

[HTML][HTML] Understanding the immunopathogenesis of COVID-19: Its implication for therapeutic strategy

Y Shimizu - World journal of clinical cases, 2020 - ncbi.nlm.nih.gov
Although 80% of individuals infected with the severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2) recover without antiviral treatments, the other 20% progress to …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

Understanding COVID-19 pandemic: molecular mechanisms and potential therapeutic strategies. An evidence-based review

R Hanna, S Dalvi, T Sălăgean, ID Pop… - Journal of …, 2021 - Taylor & Francis
Abstract Initially, the SARS-CoV-2 virus was considered as a pneumonia virus; however, a
series of peer reviewed medical papers published in the last eight months suggest that this …

Autoimmune and rheumatic manifestations associated with COVID-19 in adults: an updated systematic review

KT Tang, BC Hsu, DY Chen - Frontiers in immunology, 2021 - frontiersin.org
Background: Numerous cases of the coronavirus disease 2019 (COVID-19) with
autoimmune and rheumatic manifestations have been reported. Despite the available …

Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
In December 2019, a novel coronavirus, COVID-19, was discovered to be the causal agent
of a severe respiratory infection named SARS-CoV-2, and it has since been recognized …

Immunomodulatory agents for COVID-19 treatment: possible mechanism of action and immunopathology features

F Rommasi, MJ Nasiri, M Mirsaeidi - Molecular and cellular biochemistry, 2022 - Springer
The novel coronavirus pandemic has emerged as one of the significant medical-health
challenges of the current century. The World Health Organization has named this new virus …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …

The impact of pre-existing comorbidities and therapeutic interventions on COVID-19

LA Callender, M Curran, SM Bates… - Frontiers in …, 2020 - frontiersin.org
Evidence from the global outbreak of SARS-CoV-2 has clearly demonstrated that individuals
with pre-existing comorbidities are at a much greater risk of dying from COVID-19. This is of …