Genetic analysis of the atrial natriuretic peptide gene in essential hypertension

N KATO, T SUGIYAMA, H MORITA, T NABIKA… - Clinical …, 2000 - portlandpress.com
Atrial natriuretic peptide (ANP) plays an important role in the regulation of blood pressure
through sodium–water homoeostasis. Accordingly, several investigators have raised the …

Association study between the variants of the human ANP gene and essential hypertension

D Rahmutula, T Nakayama, M Soma… - Hypertension …, 2001 - jstage.jst.go.jp
抄録 Variants of atrial natriuretic peptide (ANP) are reported to be more common in blacks
with hypertension than in normotensive controls and constitute an independent risk factor for …

Atrial natriuretic peptide (ANP) gene promoter variant and increased susceptibility to early development of hypertension in humans

S Rubattu, A Evangelista, D Barbato, G Barba… - Journal of human …, 2007 - nature.com
Previous evidence supports a role of atrial natriuretic peptide (ANP) as a candidate gene for
hypertension. We characterized an ANP gene promoter variant, which has been associated …

Atrial natriuretic peptide gene promoter polymorphism is associated with left ventricular hypertrophy in hypertension

H Xue, S Wang, H Wang, K Sun, X Song… - Clinical …, 2008 - portlandpress.com
Recent studies suggest that the ANP (atrial natriuretic peptide)/NPRA (type A natriuretic
peptide receptor) system modulates ventricular remodelling and cardiac hypertrophy in …

HpaII polymorphism in the atrial natriuretic peptide gene and hypertension

BMY Cheung, R Leung, S Shiu, KCB Tan… - American journal of …, 1999 - academic.oup.com
This was an association study of genetic polymorphisms to compare the distribution of the
genotypes and alleles of the Hpa II polymorphism of the atrial natriuretic peptide (ANP) gene …

Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension

S Rubattu, G Bigatti, A Evangelista, C Lanzani… - Journal of the American …, 2006 - jacc.org
Objectives: The goal of our study was to investigate the relationships between atrial
natriuretic peptide (ANP), brain natriuretic peptide (BNP), and type A natriuretic peptide …

A review of the role of atrial natriuretic peptide gene polymorphisms in hypertension and its sequelae

AI Lynch, SA Claas, DK Arnett - Current hypertension reports, 2009 - Springer
The natriuretic peptide precursor A (NPPA) gene, found on chromosome 1p36, encodes the
precursor from which atrial natriuretic polypeptide (ANP) is derived. Due to the action of …

Hpa II polymorphism of the atrial natriuretic peptide gene and the blood pressure response to salt intake in normotensive men

U Schorr, J Beige, J Ringel, S Turan… - Journal of …, 1997 - journals.lww.com
Objective To test the hypothesis that the Hpa II variant of the atrial natriuretic peptide gene
(ANP), which has been reported to be more common among black hypertensives than it is …

Genome-wide association study implicates atrial natriuretic peptide rather than B-type natriuretic peptide in the regulation of blood pressure in the general population

PP Salo, AS Havulinna, T Tukiainen… - Circulation …, 2017 - Am Heart Assoc
Background—Cardiomyocytes secrete atrial natriuretic peptide (ANP) and B-type natriuretic
peptide (BNP) in response to mechanical stretching, making them useful clinical biomarkers …

Atrial natriuretic peptide gene variants and circulating levels: implications in cardiovascular diseases

S Rubattu, S Sciarretta, M Volpe - Clinical Science, 2014 - portlandpress.com
ANP (atrial natriuretic peptide), discovered 30 years ago in rat cardiac atria, has been
extensively investigated with regard to physiology, pathophysiology, cardiovascular disease …