Construction and Verification of the Molecular Subtype and a Novel Prognostic Signature Based on Inflammatory Response-Related Genes in Uveal Melanoma

F Zhang, Y Deng, D Wang, S Wang - Journal of Clinical Medicine, 2023 - mdpi.com
The significance of inflammation in tumorigenesis and progression has become prominent.
This study aimed to construct and validate the molecular subtype and a novel prognostic …

Construction and validation of a novel immunosignature for overall survival in uveal melanoma

C Gu, X Gu, Y Wang, Z Yao, C Zhou - Frontiers in Cell and …, 2021 - frontiersin.org
Objectives Uveal melanoma (UM) is the most common primary intraocular malignancy in
adults, and immune infiltration plays a crucial role in the prognosis of UM. This study aimed …

Identification of a prognostic six-immune-gene signature and a nomogram model for uveal melanoma

B Yang, Y Fan, R Liang, Y Wu, A Gu - BMC ophthalmology, 2023 - Springer
Background To identify an immune-related prognostic signature and find potential
therapeutic targets for uveal melanoma. Methods The RNA-sequencing data obtained from …

[HTML][HTML] Identification of an immune-related signature for the prognosis of uveal melanoma

YZ Li, Y Huang, XY Deng, CS Tu - International Journal of …, 2020 - ncbi.nlm.nih.gov
AIM To construct an immune-related prognostic signature (IPS) that can distinguish and
predict prognosis in uveal melanoma (UM). METHODS The transcriptomic data and …

Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk …

W Wang, H Zhao, S Wang - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Uveal melanoma (UVM) is the most invasive intraocular malignancy in adults
with a poor prognosis. Growing evidence revealed that immune-related gene is related to …

Integrated analysis of genes associated with immune microenvironment and distant metastasis in uveal melanoma

W Zhou, J Li - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Inflammatory infiltration plays an essential role in the progression of tumor malignancy. The
aim of this study was to identify genes associated with inflammatory microenvironment and …

Immunogenic profiling of metastatic uveal melanoma discerns a potential signature related to prognosis

J Wang, M Liu, J Sun, Z Zhang - Journal of Cancer Research and Clinical …, 2024 - Springer
Background Uveal melanoma (UM) is an aggressive intraocular malignant tumor. The
present study aimed to identify the key genes associated with UM metastasis and …

The prognostic value of immune-related genes AZGP1, SLCO5A1, and CTF1 in Uveal melanoma

W Wang, S Wang - Frontiers in Oncology, 2022 - frontiersin.org
Objective Uveal melanoma (UM) is an aggressive malignancy with a poor prognosis and no
available effective treatment. Therefore, exploring a potential prognostic marker for UM …

A comprehensive prognostic and immunological analysis of a six-gene signature associated with glycolysis and immune response in uveal melanoma

J Liu, J Lu, W Li - Frontiers in immunology, 2021 - frontiersin.org
Uveal melanoma (UM) is a subtype of melanoma with poor prognosis. This study aimed to
construct a new prognostic gene signature that can be used for survival prediction and risk …

Identification of precise therapeutic targets and characteristic prognostic genes based on immune gene characteristics in uveal melanoma

Z Zhang, J Su, L Li, W Du - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
The tumor microenvironment is an important factor for the immunotherapy of tumor patients.
The sequenced transcriptome data can be used to describe the tumor microenvironment …