Background Pairing of homologous chromosomes at meiosis is an important requirement for
recombination and balanced chromosome segregation among the products of meiotic …

Mnd1 has recently been identified in yeast as a key player in meiotic recombination. Here
we describe the identification and functional characterisation of the Arabidopsis homologue …

The efficient repair of double-strand breaks (DSBs) in genomic DNA is crucial for the survival
of all organisms. Mnd1 is suggested to promote the strand invasion step during meiotic …

During meiosis, each chromosome must pair with its homolog and undergo meiotic
crossover recombination in order to segregate properly at the first meiotic division …

The hop2 mutant of Saccharomyces cerevisiae arrests in meiosis with extensive
synaptonemal complex (SC) formation between nonhomologous chromosomes. A screen …

The initiation of meiotic recombination by the formation of DNA double‐strand breaks
(DSBs) catalysed by the Spo11 protein is strongly evolutionary conserved. In …

During meiosis, homologous recombination (HR) is essential to repair programmed DNA
double-strand breaks (DSBs), and a dedicated protein machinery ensures that the …

In yeast, the DMC1 gene is required for interhomolog recombination, which is an essential
step for bivalent formation and the correct partition of chromosomes during meiosis I. By …

Meiotic recombination starts with the programmed formation of double-strand breaks (DSB)
in DNA, which are catalyzed by SPO11, a type II topoisomerase that is evolutionarily …

PRDM9 directs human meiotic crossover hot spots to intergenic sequence motifs, whereas
budding yeast hot spots overlap regions of low nucleosome density (LND) in gene …