[PDF][PDF] There is no fundamental trade-off between prediction accuracy and feature importance reliability

J Chen, LQR Ooi, J Li, CL Asplund, SB Eickhoff… - bioRxiv, 2022 - juser.fz-juelich.de
There is significant interest in using neuroimaging data to predict behavior. The predictive
models are often interpreted by the computation of feature importance, which quantifies the …

[HTML][HTML] Relationship between prediction accuracy and feature importance reliability: An empirical and theoretical study

J Chen, LQR Ooi, TWK Tan, S Zhang, J Li, CL Asplund… - NeuroImage, 2023 - Elsevier
There is significant interest in using neuroimaging data to predict behavior. The predictive
models are often interpreted by the computation of feature importance, which quantifies the …

The burden of reliability: How measurement noise limits brain-behaviour predictions

M Gell, SB Eickhoff, A Omidvarnia, V Küppers, KR Patil… - BioRxiv, 2023 - biorxiv.org
Current major efforts in human neuroimaging research aim to understand individual
differences and identify biomarkers for clinical applications. One particularly promising …

[HTML][HTML] Reliability and predictability of phenotype information from functional connectivity in large imaging datasets

J Dafflon, D Moraczewski, E Earl, DM Nielson… - ArXiv, 2024 - ncbi.nlm.nih.gov
One of the central objectives of contemporary neuroimaging research is to create predictive
models that can disentangle the connection between patterns of functional connectivity …

[HTML][HTML] Power and reproducibility in the external validation of brain-phenotype predictions

M Rosenblatt, L Tejavibulya, CC Camp, R Jiang… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Identifying reproducible and generalizable brain-phenotype associations is a central goal of
neuroimaging. Consistent with this goal, prediction frameworks evaluate brain-phenotype …

The Bayesian polyvertex score (PVS-B): a whole-brain phenotypic prediction framework for neuroimaging studies

W Zhao, CE Palmer, W Thompson, TL Jernigan… - BioRxiv, 2019 - biorxiv.org
The traditional brain mapping approach has greatly advanced our understanding of the
localized effect of the brain on behavior. However, the statistically significant brain regions …

[HTML][HTML] Machine learning prediction of cognition from functional connectivity: Are feature weights reliable?

Y Tian, A Zalesky - NeuroImage, 2021 - Elsevier
Cognitive performance can be predicted from an individual's functional brain connectivity
with modest accuracy using machine learning approaches. As yet, however, predictive …

Interpreting Brain Biomarkers: Challenges and solutions in interpreting machine learning-based predictive neuroimaging

R Jiang, CW Woo, S Qi, J Wu… - IEEE signal processing …, 2022 - ieeexplore.ieee.org
Predictive modeling of neuroimaging data (predictive neuroimaging) for evaluating
individual differences in various behavioral phenotypes and clinical outcomes is of growing …

[HTML][HTML] Beyond fingerprinting: Choosing predictive connectomes over reliable connectomes

ES Finn, MD Rosenberg - NeuroImage, 2021 - Elsevier
Recent years have seen a surge of research on variability in functional brain connectivity
within and between individuals, with encouraging progress toward understanding the …

[HTML][HTML] Brain-phenotype predictions can survive across diverse real-world data

BD Adkinson, M Rosenblatt, J Dadashkarimi… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Recent work suggests that machine learning models predicting psychiatric treatment
outcomes based on clinical data may fail when applied to unharmonized samples …