Abstract Metallo‐β‐lactamases (MBLs) cause resistance of Gram‐negative bacteria to β‐
lactam antibiotics and are of serious concern, because they can inactivate the last‐resort …

Abstract Metallo-β-lactamases (MBLs) represent an increasingly serious threat to public
health because of their increased prevalence worldwide in relevant opportunistic Gram …

In Gram-negative bacteria, the major mechanism of resistance to β-lactam antibiotics is the
production of one or several β-lactamases (BLs), including the highly worrying …

Resistance to β-lactam antibiotics in Gram-negatives producing metallo-β-lactamases
(MBLs) represents a major medical threat and there is an extremely urgent need to develop …

Metallo-β-lactamases (MBLs) contribute to the resistance of Gram-negative bacteria to
carbapenems, last-resort antibiotics at hospital, and MBL inhibitors are urgently needed to …

Metallo-β-lactamases (MBLs) are zinc-dependent enzymes capable of hydrolyzing all
bicyclic β-lactam antibiotics, posing a great threat to public health. However, there are …

Abstract Metallo-β-lactamases (MBLs) are important contributors of Gram-negative bacteria
resistance to β-lactam antibiotics. MBLs are highly worrying because of their …

Abstract Metallo‐β‐lactamases (MBLs) are zinc‐dependent bacterial enzymes that
inactivate essentially all classes of β‐lactam antibiotics including last‐resort carbapenems …

Abstract Metallo‐β‐lactamases (MBLs) are increasingly involved as a major mechanism of
resistance to carbapenems in relevant opportunistic Gram‐negative pathogens …

Multidrug-resistant bacterial infections have become in recent years an increasingly
worrisome problem in the medical community. The β-lactams are the most used antibiotics …