[HTML][HTML] Overview of the pathogenesis of COVID‑19

C Li, Q He, H Qian, J Liu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
At present, the pathogenesis of the novel coronavirus disease 2019 (COVID‑19) has not
been fully elucidated. Clinical and experimental findings from studies investigating COVID …

[HTML][HTML] Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the pandemic coronavirus disease-2019 (COVID-19), which can lead to …

[HTML][HTML] Different innate and adaptive immune responses to SARS-CoV-2 infection of asymptomatic, mild, and severe cases

R Carsetti, S Zaffina, E Piano Mortari, S Terreri… - Frontiers in …, 2020 - frontiersin.org
SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum
of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to …

[HTML][HTML] SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”

BL Sievers, MTK Cheng, K Csiba, B Meng… - Cellular & Molecular …, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

[HTML][HTML] Inflammation and antiviral immune response associated with severe progression of COVID-19

Q Zhang, Y Meng, K Wang, X Zhang, W Chen… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease-2019 (COVID-19) is a novel respiratory disease induced by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It remains poorly understood how …

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

Y Jamilloux, T Henry, A Belot, S Viel, M Fauter… - Autoimmunity …, 2020 - Elsevier
The coronavirus disease-19 pandemic (COVID-19), which appeared in China in December
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …

Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism

M Policard, S Jain, S Rego, S Dakshanamurthy - Virus Research, 2021 - Elsevier
The spread of SARS-CoV-2 and the increasing mortality rates of COVID-19 create an urgent
need for treatments, which are currently lacking. Although vaccines have been approved by …

[HTML][HTML] Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …

[HTML][HTML] Humoral immune responses in COVID-19 patients: a window on the state of the art

G Siracusano, C Pastori, L Lopalco - Frontiers in immunology, 2020 - frontiersin.org
The novel SARS-CoV-2 is a recently emerging virus causing a human pandemic. A great
variety of symptoms associated with COVID-19 disease, ranging from mild to severe …