OS Pedersen, EB Pedersen - Antiviral Chemistry and …, 1999 - journals.sagepub.com
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are promising drugs for the treatment of HIV when used in combination with other anti-HIV drugs such as nucleoside …
P Zhan, X Liu - Expert opinion on therapeutic patents, 2011 - Taylor & Francis
Introduction: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) form the backbone of antiretroviral treatment for many HIV-infected individuals. The unique antiviral activity, high …
Y Wang, E De Clercq, G Li - Expert opinion on drug metabolism & …, 2019 - Taylor & Francis
Introduction: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are essential components of highly active antiretroviral therapy against HIV-1 infections. Here, we provide …
G Campiani, A Ramunno, G Maga… - Current …, 2002 - ingentaconnect.com
Along with nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), nonnucleoside reverse transcriptase inhibitors (NNRTIs) have gained a definitive and …
A Blas-Garcia, JV Esplugues… - Current medicinal …, 2011 - ingentaconnect.com
Twenty years of effective clinical application have consolidated non-nucleoside reverse transcriptase inhibitors (NNRTI) as essential components of the Highly Active Antiretroviral …
Nucleoside reverse transcriptase inhibitors (NRTI) remain a cornerstone of current antiretroviral regimens in combinations usually with a nonnucleoside reverse transcriptase …
There is a need for new antiretroviral drugs with activity against HIV isolates resistant to currently available agents and improved short and long-term tolerability profiles. Clinical trial …
A Basavapathruni, KS Anderson - Current pharmaceutical …, 2006 - ingentaconnect.com
To date three nonnucleoside reverse transcriptase inhibitors (NNRTIs) have been approved by the US Food and Drug Administration for the treatment of human immunodeficiency virus …
V Joly, P Yeni - Annales de medecine interne, 2000 - europepmc.org
The non-nucleoside reverse transcriptase inhibitors (NNRTIs) directly inhibit the HIV-1 reverse transcriptase (RT) by binding in a reversible and non-competitive manner to the …