[HTML][HTML] Subcutaneous REGEN-COV antibody combination in early asymptomatic SARS-Cov-2 infection: a randomized clinical trial

MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - MedRxiv, 2021 - ncbi.nlm.nih.gov
Objective: Evaluate the efficacy and safety of subcutaneous casirivimab and imdevimab
antibody combination (REGEN-COV) to prevent progression from early asymptomatic SARS …

Effect of subcutaneous casirivimab and imdevimab antibody combination vs placebo on development of symptomatic COVID-19 in early asymptomatic SARS-CoV-2 …

MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - Jama, 2022 - jamanetwork.com
Importance Easy-to-administer anti–SARS-CoV-2 treatments may be used to prevent
progression from asymptomatic infection to symptomatic disease and to reduce viral …

Subcutaneous REGEN-COV antibody combination to prevent Covid-19

MP O'Brien, E Forleo-Neto, BJ Musser… - … England Journal of …, 2021 - Mass Medical Soc
Background REGEN-COV (previously known as REGN-COV2), a combination of the
monoclonal antibodies casirivimab and imdevimab, has been shown to markedly reduce the …

REGEN-COV antibody cocktail clinical outcomes study in Covid-19 outpatients

DM Weinreich, S Sivapalasingam, T Norton, S Ali… - MedRxiv, 2021 - medrxiv.org
Background REGEN-COV antibody cocktail (casirivimab with imdevimab) rapidly reduced
viral load and decreased medically-attended visits in the phase 1/2 portion of this trial; …

REGEN-COV antibody combination and outcomes in outpatients with Covid-19

DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
Background In the phase 1–2 portion of an adaptive trial, REGEN-COV, a combination of the
monoclonal antibodies casirivimab and imdevimab, reduced the viral load and number of …

Phase 2 dose-ranging study of the virologic efficacy and safety of the combination COVID-19 antibodies casirivimab and imdevimab in the outpatient setting

C Portal-Celhay, E Forleo-Neto, W Eagan, BJ Musser… - medRxiv, 2021 - medrxiv.org
Background The monoclonal antibody combination casirivimab and imdevimab (REGEN-
COV®) reduced viral load, hospitalisation, or death when administered 1: 1 as an …

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - Medrxiv, 2021 - medrxiv.org
Background REGEN-COV is a combination of 2 monoclonal antibodies (casirivimab and
imdevimab) that bind to two different sites on the receptor binding domain of the SARS-CoV …

Effectiveness of subcutaneous casirivimab and imdevimab in ambulatory patients with COVID-19

JJ Jalbert, M Hussein, V Mastey, RJ Sanchez… - Infectious Diseases and …, 2022 - Springer
Introduction Data on real-world effectiveness of subcutaneous (SC) casirivimab and
imdevimab (CAS+ IMD) for the treatment of coronavirus disease 2019 (COVID-19) are …

Effectiveness of REGEN-COV antibody combination in preventing severe COVID-19 outcomes

S Hayek, Y Ben-Shlomo, N Dagan, BY Reis… - Nature …, 2022 - nature.com
REGEN-COV, a combination of the monoclonal antibodies casirivimab and imdevimab, has
been approved as a treatment for high-risk patients infected with SARS-CoV-2 within five …

[HTML][HTML] Emergent inpatient administration of casirivimab and imdevimab antibody cocktail for the treatment of COVID-19 pneumonia

AT Phan, J Gukasyan, S Arabian, S Wang, MM Neeki - Cureus, 2021 - ncbi.nlm.nih.gov
Infection by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) is known to
have the highest mortality rate among the elderly and those with pre-existing medical …