In an earlier publication, a binary classification of chronic diseases has been proposed.
Chronic diseases were classified as “high Treg” or “low Treg” diseases depending on …

Cancer cells escape immune recognition by exploiting the programmed cell‐death protein 1
(PD‐1)/programmed cell‐death 1 ligand 1 (PD‐L1) immune checkpoint axis. Immune …

The tumor microenvironment (TME)–a term comprising non‐neoplastic cells and
extracellular matrix as well as various cytokines, chemokines, growth factors, and other …

Evasion of immune destruction is considered one of the hallmarks of cancer. Chronic
inflammation can enable immune escape by suppressing immune surveillance and …

As patients continue to die from malignant lymphoma, novel treatment options continue to be
warranted. To successfully grow and spread, tumor cells need to escape the immune …

The survival and growth of lymphoma cells relies on suppression of antitumor immunity
through interactions between the tumor microenvironment and lymphoma cells. These are …

To evade elimination by the host immune system, tumor cells commonly exploit
physiological immune checkpoint pathways, restraining efficient anti-tumor immune cell …

Simple Summary Inflammation has been recognized to be linked to tumor development.
Several markers of inflammation can be detected via blood such as variety of blood cells …

A link between chronic inflammation and development of tumors is well established.
Moreover, it has become evident that tumorigenesis is not a cell autonomous disease, and …

The development of immune checkpoint blockade (ICB)-based immunotherapy has
dramatically changed methods of cancer treatment. This approach triggers a durable …