Immunomodulatory therapies for COVID-19 in solid organ transplant recipients

M Fernández-Ruiz, JM Aguado - Current Transplantation Reports, 2020 - Springer
Abstract Purpose of Review Severe coronavirus disease 2019 (COVID-19) is characterized
by the development of a deleterious hyperinflammatory response, in which the pleiotropic …

A retrospective matched cohort single‐center study evaluating outcomes of COVID‐19 and the impact of immunomodulation on COVID‐19‐related cytokine release …

M Ringer, V Azmy, K Kaman, D Tang… - Transplant Infectious …, 2021 - Wiley Online Library
This retrospective matched cohort study describes 30 solid organ transplant (SOT) patients
with Coronavirus Disease 2019 (COVID‐19) matched 1: 2 to 60 non‐SOT patients (control …

Use of tocilizumab in kidney transplant recipients with COVID‐19

MJ Pérez‐Sáez, M Blasco… - American Journal of …, 2020 - Wiley Online Library
Acute respiratory distress syndrome associated with coronavirus infection is related to a
cytokine storm with large interleukin‐6 (IL‐6) release. The IL‐6‐receptor blocker tocilizumab …

[HTML][HTML] Tocilizumab therapy in 5 solid and composite tissue transplant recipients with early ARDS due to SARS-CoV-2

JA Morillas, FM Canosa, P Srinivas, T Asadi… - American Journal of …, 2020 - Elsevier
There are emerging data depicting the clinical presentation of coronavirus disease 19
(COVID-19) in solid organ transplant recipients but negligible data-driven guidance on …

Effect of immunosuppression maintenance in solid organ transplant recipients with COVID‐19: systematic review and meta‐analysis

A Karruli, S Spiezia, F Boccia… - Transplant Infectious …, 2021 - Wiley Online Library
Background The aim of this study was to assess the effect of continuing immune suppressive
therapy in solid organ transplant recipients (SOTR) with coronavirus disease 2019 (COVID …

COVID-19 therapeutics for solid organ transplant recipients; 6 months into the pandemic: where are we now?

RK Avery - Transplantation, 2021 - journals.lww.com
As in the general population with coronavirus 2019 (COVID-19) infection, therapeutic
interventions in solid organ transplant (SOT) recipients have evolved over time. The …

[HTML][HTML] COVID-19 in patients with solid organ transplantation: a systematic review

R Hage, C Steinack, C Benden, MM Schuurmans - Transplantology, 2020 - mdpi.com
The novel coronavirus, SARS-CoV-2, is causing a pandemic of unknown precedent, with
huge healthcare challenges and worldwide disruptions to economic and social life. Lung …

Clinical course of COVID‐19 in a liver transplant recipient on hemodialysis and response to tocilizumab therapy: a case report

MB Hammami, B Garibaldi, P Shah… - American Journal of …, 2020 - Wiley Online Library
The novel coronavirus disease 2019 (COVID‐19) is a highly infectious and rapidly
spreading disease. There are limited published data on the epidemiology and outcomes of …

Immunomodulators for severe coronavirus disease‐2019 in transplant patients: Do they increase the risk of secondary infection?

MA Mendoza, N Ranganath… - Transplant Infectious …, 2023 - Wiley Online Library
Background Current guidelines recommend immunomodulators, tocilizumab or baricitinib,
for the management of severe coronavirus disease‐2019 (COVID‐19) in patients with …

SARS-CoV-2 in solid organ transplant recipients: a structured review of 2020

M Quante, L Brake, A Tolios, A Della Penna… - Transplantation …, 2021 - Elsevier
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
is challenging health systems all over the world. Particularly high-risk groups show …