Obesity increases the risks of developing cardiovascular and metabolic diseases and
degrades quality of life, ultimately increasing the risk of death. However, not all forms of …

Objective To review recent advances in understanding the cellular mechanisms that
regulate fat distribution. Methods In this review, new insights into depot and sex differences …

Obesity is linked to numerous comorbidities that include, but are not limited to, glucose
intolerance, insulin resistance, dyslipidemia, and cardiovascular disease. Current evidence …

This review focuses on the human genetics, epidemiology, and molecular pathophysiology
of sex differences in central obesity, adipose distribution, and related cardiometabolic …

Background Body fat distribution is, next to overall obesity, an important risk factor for
cardiometabolic outcomes in the general population. In particular, visceral adipose tissue …

Obesity and associated metabolic co-morbidities are a worldwide public health problem.
Negative health outcomes associated with obesity, however, do not arise from excessive …

An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

Obesity is an excess accumulation of adipose tissue mass, and, together with its sequelae,
in particular type II diabetes and metabolic syndrome, obesity presents a major health crisis …

Fat stored in visceral depots makes obese individuals more prone to complications than
subcutaneous fat. There is good evidence that body fat distribution (FD) is controlled by …

Although an individual's total fat mass predicts morbidities such as coronary artery disease
and diabetes, the anatomical distribution of adipose tissue is a strong and independent …