MUC1 is a highly glycosylated transmembrane mucin on the luminal surface of epithelial
cells, protecting them from extreme factors. In cancer cells, MUC1 expression is upregulated …

MUC1 is a mucin family protein, overexpressed in more than 90% of breast cancers in an
underglycosylated form, exposing the core peptides of the extracellular domain that act as a …

The overexpression and aberrant glycosylation of MUC1 is associated with a wide variety of
cancers, making it an ideal target for immunotherapeutic strategies. This review highlights …

MUC1 is a glycoprotein that is overexpressed in tumor cells. In normal cells it forms a
protective layer against microbes and toxic chemicals, besides providing lubrication on …

Abstract Mucin 1 (MUC1) was the first discovered transmembrane protein of the mucin
family; it normally covers epithelial cells of the mucous membrane, providing lubrication and …

The transmembrane glycoprotein Mucin 1 (MUC1) is aberrantly glycosylated and
overexpressed in a variety of epithelial cancers, and plays a crucial role in progression of …

MUC1 is a large trans-membrane highly glycosylated mucin which is expressed at the apical
pole of normal cells in glandular epithelia. MUC1 is implicated in many physiological …

The MUC1 protein is aberrantly expressed on many solid tumor cancers. In contrast to its
apical clustering on healthy epithelial cells, it is uniformly distributed over cancer cells …

Mucin1 is a highly glycosylated type 1 transmembrane mucin that ranks second among 75
tumor-related antigens published by the National Cancer Institute, and has been identified …

The MUC1 oncoprotein is aberrantly expressed at high levels in most human carcinomas
and certain hematologic malignancies. 1 Estimates are that, of the 1.4 million tumors …