Authenticating DNA extracted from ancient skeletal remains

MB Richards, BC Sykes, REM Hedges - Journal of Archaeological Science, 1995 - Elsevier
The survival of DNA, the most informative biological molecule, for periods of at least several
thousand years in bone was demonstrated more than four years ago. However, difficulties …

Ancient DNA applications in human osteoarchaeology: achievements, problems and potential

K Brown - Human Osteology in Archaeology and Forensic …, 2000 - books.google.com
The discovery of the structure of DNA in 1953 heralded a new era in biological sciences and
has had profound implications for many other disciplines. The double helix structure …

DNA in ancient bone–Where is it located and how should we extract it?

PF Campos, OE Craig, G Turner-Walker… - Annals of Anatomy …, 2012 - Elsevier
Despite the widespread use of bones in ancient DNA (aDNA) studies, relatively little
concrete information exists in regard to how the DNA in mineralised collagen degrades, or …

Progress in forensic bone DNA analysis: Lessons learned from ancient DNA

M Hofreiter, J Sneberger, M Pospisek… - Forensic Science …, 2021 - Elsevier
Research on ancient and forensic DNA is related in many ways, and the two fields must deal
with similar obstacles. Therefore, communication between these two communities has the …

Evidence of authentic DNA from Danish Viking Age skeletons untouched by humans for 1,000 years

L Melchior, T Kivisild, N Lynnerup, J Dissing - PLoS One, 2008 - journals.plos.org
Background Given the relative abundance of modern human DNA and the inherent
impossibility for incontestable proof of authenticity, results obtained on ancient human DNA …

One of the key characteristics of ancient DNA, low copy number, may be a product of its extraction

JL Barta, C Monroe, JE Teisberg, M Winters… - Journal of …, 2014 - Elsevier
DNA from ancient sources is generally believed to be of low copy number, despite minimal
attention towards direct measurement of DNA loss accumulated through the extraction …

More on contamination: the use of asymmetric molecular behavior to identify authentic ancient human DNA

H Malmström, EM Svensson, MTP Gilbert… - Molecular biology …, 2007 - academic.oup.com
Authentication of ancient human DNA results is an exceedingly difficult challenge due to the
presence of modern contaminant DNA sequences. Nevertheless, the field of ancient human …

DNA survivability in skeletal remains

KE Latham, ME Madonna, JL Hipp - Manual of forensic …, 2021 - taylorfrancis.com
The purification and analysis of DNA from skeletal material has numerous applications in
archeological and forensic contexts. The degree of degradation of the DNA contained within …

Ancient DNA in anthropology: methods, applications, and ethics

FA Kaestle, KA Horsburgh - American Journal of Physical …, 2002 - Wiley Online Library
Anthropologists were quick to recognize the potential of new techniques in molecular
biology to provide additional lines of evidence on questions long investigated in …

Sampling skeletal remains for ancient DNA (aDNA): a measure of success

MD Leney - Historical Archaeology, 2006 - Springer
More than 2,000 samples of human osseous and dental materials drawn from forensic
archaeological casework of the Joint POW/MIA Accounting Command Central Identification …