Background/Aims: Diabetic cardiomyopathy (DCM) is a common complication of diabetes
and can cause heart failure, arrhythmia and sudden death. The pathogenesis of DCM …

Diabetes cardiomyopathy (DCM) is a critical complication of long-term chronic diabetes
mellitus and is characterized by myocardial fibrosis and myocardial hypertrophy. It has been …

Diabetic corneal endothelial keratopathy is an intractable ocular complication characterized
by corneal edema and endothelial decompensation, which seriously threaten vision. It has …

Myocardial dysfunction is a prime cause of death in sepsis. This study is to delve into the
function of lncRNA KCNQ1OT1 in myocardial injury induced by sepsis. Sepsis-induced …

Aims Doxorubicin (DOX), a widely used powerful chemotherapeutic component for cancer
treatment, can give rise to severe cardiotoxicity that limits its clinical use. Pyroptosis is …

Abstract N6-methyladenosine (m6A) is one of the most important epigenetic regulation of
RNAs, such as lncRNAs. However, the underlying regulatory mechanism of m6A in diabetic …

Background Long noncoding RNAs (lncRNAs) can regulate the progression of DN. This
research aimed to study the effect of lncRNA KCNQ1OT1 on the oxidative stress and …

Diabetic cardiomyopathy is a common cardiac condition in patients with diabetes mellitus,
which can result in cardiac hypertrophy and subsequent heart failure, associated with …

Background Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)
inflammasome is associated with metabolic disorder and cell death, which are important …

This study aimed to investigate the protective effects of long non-coding RNA KCNQ1OT1
against myocardial ischemia/reperfusion (I/R) injury following acute myocardial infarction, as …