Molecular biomarkers for the early detection of ovarian cancer

R Zhang, MKY Siu, HYS Ngan, KKL Chan - International Journal of …, 2022 - mdpi.com
Ovarian cancer is the deadliest gynecological cancer, leading to over 152,000 deaths each
year. A late diagnosis is the primary factor causing a poor prognosis of ovarian cancer and …

Clinical significance of the CD98hc-CD147 complex in ovarian cancer: a bioinformatics analysis

XY Zhou, JY Li, JT Tan, YL HuangLi… - Journal of Obstetrics …, 2023 - Taylor & Francis
Ovarian cancer is one of the most common malignant tumours affecting the female
reproductive organs. CD147 (BSG) and CD98hc (SLC3A2) are oncogenes that form the …

Identification of candidate biomarkers and analysis of prognostic values in ovarian cancer by integrated bioinformatics analysis

Z Xu, Y Zhou, Y Cao, TLA Dinh, J Wan, M Zhao - Medical oncology, 2016 - Springer
Ovarian cancer is the first leading cause of mortality in gynecological malignancies. To
identify key genes and microRNAs in ovarian cancer, mRNA microarray dataset GSE36668 …

[HTML][HTML] Identification of solute-carrier family 27A molecules (SCL27As) as a potential biomarker of ovarian cancer based on bioinformatics and experiments

H Chen, T Han, Y Zhao, L Feng - Annals of translational medicine, 2021 - ncbi.nlm.nih.gov
Background Ovarian cancer is one of the 3 major gynecological malignancies with high
mortality, poor prognosis, and lack of specific diagnostic and prognostic markers. Solute …

Combined serum DKK3 and circulating CD133 cells as prognostic biomarkers for ovarian cancer patients

XC Nie, F He, C Lan, JM Niu, P Xia - OncoTargets and therapy, 2021 - Taylor & Francis
Introduction Ovarian cancer (OV) can seriously endanger women's physical and mental
health. Serum DKK3 has been used for the diagnosis and prognosis of patients with ovarian …

[HTML][HTML] Promotion of ovarian cancer cell invasion, migration and colony formation by the miR‑21/Wnt/CD44v6 pathway

Y Wang, X Yang, M Yuan, S Xian… - Oncology …, 2019 - spandidos-publications.com
Ovarian cancer (OC) has the highest mortality rate among female malignant tumors, and OC
commonly relapses and metastasizes. The mechanisms underlying the occurrence and …

TTK (threonine tyrosine kinase) regulates the malignant behaviors of cancer cells and is regulated by microRNA-582-5p in ovarian cancer

N Lu, L Ren - Bioengineered, 2021 - Taylor & Francis
There is growing evidence that threonine tyrosine kinase (TTK) dysregulation is linked to the
progression of multiple malignancies. Nonetheless, the role of TTK in ovarian cancer (OC) …

High Expression of miR-532-5p, a Tumor Suppressor, Leads to Better Prognosis in Ovarian Cancer Both In Vivo and In Vitro

F Wang, JTH Chang, CJ Kao, RS Huang - Molecular cancer therapeutics, 2016 - AACR
Ovarian cancer is the leading cause of death for gynecologic cancers, ranking fifth overall for
cancer-related death among women. The identification of biomarkers and the elucidation of …

[HTML][HTML] The oncogenic and prognostic role of PDK1 in the progression and metastasis of ovarian cancer

S Yao, W Shang, L Huang, R Xu, M Wu… - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the most lethal of gynecological tumors in women. Tumor
metabolism has become a new opportunity in the treatment of tumors. Pyruvate …

[HTML][HTML] MiR-143 inhibits endometrial cancer cell proliferation and metastasis by targeting MAPK1

L Chang, D Zhang, H Shi, Y Bian, R Guo - Oncotarget, 2017 - ncbi.nlm.nih.gov
Endometrial cancer (EC) is one of the most commonly diagnosed gynecologic malignancies
in the world, with the morbidity rate of over 7%. The mechanism of the pathogenesis has not …