Background To investigate the longitudinal relationship between physical frailty, the clinical
representation of accelerated biological aging, and antidepressant medication response in …

Introduction Depressive disorder has been conceptualised as a condition of accelerated
biological ageing. We operationalised a frailty index (FI) as marker for biological ageing …

Frailty and depression are important issues affecting older adults. Depressive syndrome
may be difficult to clinically disambiguate from frailty in advanced old age. Current reviews …

Objectives Accumulating evidence shows depression as a risk factor for frailty, but studies
are mainly population-based and widely differ in their assessment of either depression or …

Objective: Frailty is a clinical phenotype that predicts negative health outcomes, including
mortality, and is increasingly used for risk stratification in geriatric medicine. Similar to frailty …

Objective To investigate the relationship between frailty and treatment response to
antidepressant medications in adults with late life depression (LLD). Methods Data were …

Background Depression and frailty both predict disability and morbidity in later life. However,
it is unclear to what extent these common geriatric syndromes represent overlapping …

Background Many of the symptoms, consequences, and risk factors for frailty are shared with
late‐life depression. However, thus far, few studies have addressed the conceptual and …

Although the public importance of frailty is widely acknowledged by the World Health
Organization, physical frailty is still largely neglected in geriatric mental health care. Firstly in …

Background Frailty and depressive symptoms are common issues facing older adults and
may be associated. Objectives To determine if:(i) depressive symptoms are associated with …