We have demonstrated that the subcellular targeting properties of the indole-based
cyanines can be tuned by the functional substituent attached onto the indole moiety in which …

The conveniently obtained water-soluble small-molecule L1–5 were selective for RNA with
remarkable “off–on” two-photon fluorescence responses in vitro and in vivo, showing that L1 …

RNA-binding small probes with deep-red emission are promising for RNA analysis in
biological media without suffering from background fluorescence. Here benzo [c, d] indole …

We have synthesized a two-photon organic small-molecule probe (DMI), which has a
considerable two-photon absorption cross section (δ) value and selectively stained …

A two-photon fluorescent probe (J1) that selectively stains intracellular nucleolar RNA was
screened from three water-soluble terpyridine derivatives (J1–J3) with quaternary …

RNA-based fluorescent probes are currently limited by their low selectivity toward RNA
versus DNA, and low specificity to different RNA structures. Poor membrane permeability is …

Two low molecular weight, indole-based, mono-cationic probes, were designed and
synthesized. According to their spectral response to ribonucleic acid in vitro and direct …

Small molecular weight probes that can show a fluorescence signaling response upon
binding to RNAs are promising for RNA imaging in living cells. Live-cell RNA imaging …

We have synthesized four indole derivatives (INS1, IND1, INS2 and IND2) successfully, and
experimental results of biochemical RNA fluorescence assays and direct intracellular …

We present the design and synthesis of water-soluble quinoline–indole-based derivatives
(IM-1, IM-2, and IM-3) with three-photon absorption activity. IM-3 can specifically target DNA …