Evaluation of Mutations in 23S rRNA, rdxA and frxA Genes of Helicobacter pylori in Paraffin-Embedded Gastric Biopsy Specimens from Iranian Gastric Cancer and …

S Beheshtirouy, S Eyvazi, V Tarhriz - Journal of Gastrointestinal Cancer, 2021 - Springer
Purpose Helicobacter pylori (H. pylori) infection is considered as one of the main cause of
gastric cancer. Treatment failure of the infection often occurs due to antibiotic resistance …

[HTML][HTML] Detection of 23SrRNA mutations strongly related to clarithromycin resistance in Helicobacter pylori strains isolated from patients in the north of Iran

Z Eghbali, A Mojtahedi, MM Ansar, SF Asl… - Jundishapur journal of …, 2016 - ncbi.nlm.nih.gov
Background: Helicobacter pylori is curved Gram negative and microaerophilic bacilli that
have infected half of the world's population. It is recognized as the causative agent of …

[HTML][HTML] The study of mutation in 23S rRNA resistance gene of Helicobacter pylori to clarithromycin in patients with gastrointestinal disorders in Isfahan—Iran

F Khademi, J Faghri, S Moghim… - Advanced biomedical …, 2014 - journals.lww.com
Background: Helicobacter pylori antimicrobial resistance is an important factor responsible
for treatment failure. The purpose of this study was evaluating the prevalence of point …

[HTML][HTML] Detection of A2142C, A2142G, and A2143G mutations in 23s rRNA gene conferring resistance to clarithromycin among Helicobacter pylori isolates in Kerman …

H Abdollahi, M Savari, MJ Zahedi… - Iranian journal of …, 2011 - ncbi.nlm.nih.gov
Background: Clarithromycin resistance in Helicbacter pylori has been found to be
associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to …

[PDF][PDF] Detection of point mutations on 23S rRNA of Helicobacter pylori and resistance to clarithromycin with PCR-RFLP in gastric biopsy specimens in Mersin, Turkey

G EMEKDAfi - Turk J Gastroenterol, 2008 - apbs.mersin.edu.tr
Background/aims: Helicobacter pylori infection has a high prevalence and is considered an
important health problem in Turkey. Unfortunately, an effective treatment has not yet been …

Prediction of Helicobacter pylori clarithromycin resistance by detection of point mutations in 23S rRNA gene

MA Soltan, MA Mansour, TI Zahir… - Egyptian Journal of …, 2018 - ejmm.journals.ekb.eg
Background: Clarithromycin is one of the most common drugs recommended as first-line
eradication therapy for H. pylori infection but the prevalence of clarithromycin resistant H …

High level of resistance to metronidazole and clarithromycin among Helicobacter pylori clinical isolates in Qazvin province, Iran

L Lormohammadi, F Nikkhahi, S Bolori, AA Karami… - Gene Reports, 2022 - Elsevier
The treatment of patients with Helicobacter pylori infection has many limitations, especially
because of antibiotic resistance. We aimed to investigate the prevalence and mechanism of …

Molecular Assessment of Resistance to Clarithromycin in Helicobacter pylori Strains Isolated from Patients with Dyspepsia by Fluorescent In Situ Hybridization in the …

J Vazirzadeh, J Falahi, S Moghim… - BioMed Research …, 2020 - Wiley Online Library
Background and Aims. Helicobacter pylori is a common infectious bacterium mostly found in
gastroduodenal diseases. The increased prevalence of clarithromycin‐resistant H. pylori …

[HTML][HTML] Evaluation of clarithromycin resistance among Iranian Helicobacter pylori isolates by E-test and real-time polymerase chain reaction methods

MH Vala, S Eyvazi, H Goudarzi, HR Sarie… - Jundishapur journal of …, 2016 - ncbi.nlm.nih.gov
Background Helicobacter pylori is an important pathogen of human gastric mucosa.
Antibiotic resistance, especially resistance to clarithromycin is a major factor for treatment …

[HTML][HTML] Detection of clarithromycin resistance and 23SrRNA point mutations in clinical isolates of Helicobacter pylori isolates: Phenotypic and molecular methods

RA Hussein, MTS Al-Ouqaili, YH Majeed - Saudi Journal of Biological …, 2022 - Elsevier
Background and objectives Peptic ulcer disease, chronic gastritis, and stomach cancer are
all caused by H. pylori. The most notable drug for the treatment is the antibiotic …