[HTML][HTML] The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

GH Meftahi, Z Jangravi, H Sahraei, Z Bahari - Inflammation Research, 2020 - Springer
Abstract Purpose Novel Coronavirus disease 2019 (COVID-19), is an acute respiratory
distress syndrome (ARDS), which is emerged in Wuhan, and recently become worldwide …

[HTML][HTML] How immunosenescence and inflammaging may contribute to hyperinflammatory syndrome in COVID-19

L Müller, S Di Benedetto - International journal of molecular sciences, 2021 - mdpi.com
Aging is characterized by the dynamic remodeling of the immune system designated
“immunosenescence,” and is associated with altered hematopoiesis, thymic involution, and …

Cytokine response in SARS-CoV-2 infection in the elderly

S Sherwani, MWA Khan - Journal of Inflammation Research, 2020 - Taylor & Francis
The last few months of 2019 witnessed the emergence, rise and rapid spread of a novel
coronavirus known as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes

M Bonafè, F Prattichizzo, A Giuliani, G Storci… - Cytokine & Growth …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized
by a high mortality of elderly men with age-related comorbidities. In most of these patients …

Immunosenescence and inflamm-ageing in COVID-19

MR Zinatizadeh, PK Zarandi, M Ghiasi… - Ageing Research …, 2023 - Elsevier
The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people
with cardiovascular disease have been proven. New findings shed light on the role of aging …

[HTML][HTML] Aging, inflammaging and immunosenescence as risk factors of severe COVID-19

AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …

[HTML][HTML] I mmunosenescence and inflammaging: risk factors of severe COVID-19 in older people

AJ Pietrobon, FME Teixeira, MN Sato - Frontiers in immunology, 2020 - frontiersin.org
Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

[HTML][HTML] Molecular and cellular immune features of aged patients with severe COVID-19 pneumonia

D Lo Tartaro, A Neroni, A Paolini, R Borella… - Communications …, 2022 - nature.com
Aging is a major risk factor for developing severe COVID-19, but few detailed data are
available concerning immunological changes after infection in aged individuals. Here we …

[HTML][HTML] A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome …

A Bektas, SH Schurman, C Franceschi, L Ferrucci - Immunity & Ageing, 2020 - Springer
A central clinical question as the world deals with the COVID-19 pandemic is what the long-
term sequelae for the millions of individuals will be who recover from the hyperinflammatory …

Aging in COVID-19: Vulnerability, immunity and intervention

Y Chen, SL Klein, BT Garibaldi, H Li, C Wu… - Ageing research …, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …